Dextromethorphan; Guaifenesin; Phenylephrine

Drug Usage Statistics, United States, 2013 - 2021

Dextromethorphan; Guaifenesin; Phenylephrine Summary for 2021

Top drug rank #0 (0)
Estimated number of prescriptions in the United States (2021) 0
Estimated number of patients in the United States (2021) 0
Average total drug cost (USD)  
Per prescription $0.00
Per day of therapy $0.00/day
Average out-of-pocket cost (USD)  
Per prescription $0.00
Per day of therapy $0.00/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 480  275
2014 469  11
2015 481  12
2016 437  44
Year Rank Change
2017 466  29
2018 493  27
2019 444  49
2020 454  10

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

No data available

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Biogtuss
  • Mucinex Fast-max
  • Presgen
  • Presgen Pediatric
  • Severe Congestion And Cough
  • Tussi Pres
  • Tussi Pres Pediatric
  • Xpecto
  • Dometuss-dmx
  • G-supress DX
  • Giltuss Cough And Cold
  • Nivanex Dmx
  • Supress DX Pediatric Drops
  • Tusicof
  • Vanatab DM
  • Actidom Dmx
  • Actinel DM
  • Alticotron
  • Altidesp
  • Altidome
  • Altipres
  • Aquanaz
  • Auromucus - Fast Maximum Severe Congestion And Cough
  • Bactimicina Cough And Cold
  • Basic Care Childrens Mucus Relief
  • Basic Care Mucus Relief Severe Congestion And Cough
  • Bio-g-tuss
  • Bio-s-pres
  • Biobron
  • Biocof
  • Biocotron
  • Biocotron-d
  • Biodesp
  • Biotpres
  • Broncotron Ped
  • Careone Childrens Mucus Relief
  • Careone Tussin CF
  • Childrens Aurotussin Cough And Cold CF
  • Childrens Cough And Cold CF
  • Childrens Mucinex
  • Childrens Mucus Relief Multi Symptom Cold
  • Childrens Multi Symptom Cold
  • Childrens Multi-symptom Cold
  • Childrens Robitussin Cough And Cold CF
  • Childrens Tussnex Multi-symptom Cold
  • Cold
  • Congestion And Cough
  • Core Values Tussin CF
  • Cvs Maximum Strength Severe Congestion And Cough
  • Deconex
  • Defensol-ito
  • Desgen
  • Desgen DM
  • Despec
  • Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride
  • DG Health Adult Tussin Multi Symptom Cold
  • DG Health Childrens Mucus Relief
  • DG Health Tussin CF
  • Equaline Childrens Mucus Relief
  • Equaline Tussin
  • Equate Childrens Multi Symptom Cold
  • Equate Tussin CF
  • Fast Acting Mucus Relief
  • Fast Maximum Severe Congestion And Cough
  • Fast Mucus Relief
  • G-tron
  • G-tron Pediatric Drops
  • G-tusicof
  • Giltuss Childrens Cough And Cold
  • Good Neighbor Pharmacy Tussin CF
  • Good Sense Childrens Mucus Relief
  • Good Sense Tussin
  • Good Sense Tussin CF
  • H E B Max Severe Congestion And Cough
  • Harris Teeter Tussin
  • Health Mart Adult Tussin
  • Igualtuss
  • Kmart - Fast Maximum Severe Congestion And Cough
  • Kroger Maximum Strength Severe Congestion And Cough
  • Leader Childrens Mucus Relief
  • Leader Tussin
  • Maximum Strength Mucus Relief Severe Congestion And Cough
  • Maximum Strength Severe Congestion And Cough
  • Maxium Strength Severe Congestion And Cough Max
  • Meijer Maximum Strength Severe Congestion And Cough
  • Mucinex Childrens
  • Mucinex Childrens Cough And Congestion
  • Mucinex Childrens Freefrom Multi-symptom Cold And Stuffy Nose
  • Mucinex Childrens Multi-symptom Cold
  • Mucinex Fast-max Severe Congestion And Cough Arctic Burst
  • Mucinex Freefrom Severe Congestion And Cough
  • Mucus Congestion And Cough Relief
  • Mucus Relief
  • Mucus Relief Congestion And Cough
  • Mucus Relief Congestion Cough
  • Mucus Relief Severe Congestion And Cough
  • Mucus Relief Severe Congestion And Cough Multi Symptom Relief
  • Multi Symptom Cold
  • Multi Symptom Cold CF
  • Multi Symptom Cold Relief CF
  • Robitussin Peak Cold Multi-symptom Cold
  • Rompe Pecho
  • Severe Congestion And Cough Max
  • Severe Congestion And Cough Relief
  • Severe Cough And Congestion
  • Severe Cough And Congestion Maximum Strength
  • Signature Care Childrens Multi Symptom Cold
  • Stona Cough
  • Sunmark Tussin CF
  • Texaclear Kids Cough And Cold
  • Topcare Childrens Mucus Relief Multi Symptom Cold
  • Topcare Mucus Relief
  • Topcare Tussin CF
  • Tukol A
  • Tukol Cough And Cold Honey Flavor
  • Tukol Cough And Congestion
  • Tukol Honey Children Cough And Congestion
  • Tukol Max Action Severe Congestion And Cough
  • Tukol Multi Symptom Cold
  • Tukol X-pecto Miel
  • Tusnel
  • Tusnel Pediatric
  • Tusnel-DM Pediatric
  • Tussin
  • Tussin CF
  • Tussin CF Multi-symptom Cold
  • Tussin Multi Symptom Cold CF
  • Tusslin
  • Tusslin TR
  • Tussnex FM Severe Cough And Congestion
  • UP And UP Maximum Strength Fast Mucus Relief
  • Vanacof DM
  • Vanacof Dmx
  • Winco Foods Childrens Multi Symptom Cold
  • Exactuss Total Release
  • Giltuss Total Release
  • Mucus Multi Symptom Cold Relief
  • Vicks
  • Vicks Childrens
  • Vicks Dayquil
  • Vicks Dayquil Kids
Generic Drug Synonyms and Salts
  • Dextromethorphan Hydrobromide; Guaifenesin; Phenylephrine Hydrochloride
  • Dextromethorphan Hydrobromide; Phenylephrine Hydrochloride; Guaifenesin
  • Guaifenesin; Dextromethorphan Hydrobromide; Phenylephrine Hydrochloride
  • Guaifenesin; Phenylephrine Hydrochloride; Dextromethorphan Hydrobromide
  • Guaifenesin; Phenylephrine; Dextromethorphan
  • Phenylephrine Hydrochloride; Dextromethorphan Hydrobromide; Guaifenesin
  • Phenylephrine Hydrochloride; Guaifenesin; Dextromethorphan Hydrobromide
  • Dextromethorphan; Guaifenesin; Phenylephrine

FDA Approval Information

Established Pharmacologic Class (EPC): Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Initial FDA approval date: 9/15/1989
First FDA applicant: Kroger Company
First dosage form: Solution (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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