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Dextromethorphan; Guaifenesin; Phenylephrine

Drug Usage Statistics, United States, 2014 - 2024

ClinCalc.com » Pharmacy » ClinCalc DrugStats » Dextromethorphan; Guaifenesin; Phenylephrine

Dextromethorphan; Guaifenesin; Phenylephrine Summary for 2024

Top drug rank #380 ( 19)
Estimated number of prescriptions in the United States (2024) 18,373
Estimated number of patients in the United States (2024) 18,373
 
Average total drug cost (USD)  
Per prescription $31.17
Per day of therapy $0.00/day
Average out-of-pocket cost (USD)  
Per prescription $31.17
Per day of therapy $0.00/day

Total Prescriptions and Patients Per Year (2014 - 2024)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2014 469  11
2015 481  12
2016 437  44
2017 466  29
2018 493  27
Year Rank Change
2019 444  49
2020 454  10
2022 341 -
2023 361  20
2024 380  19

Drug Cost Over Time (2014 - 2024)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.
  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2024)

No data available

Distribution of Days Supplied (2024)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2024)
Dextromethorphan; Promethazine 1,773,420
Codeine; Guaifenesin 1,017,179
Brompheniramine; Dextromethorphan; Pseudoephedrine 702,500
Guaifenesin 391,105
Dextromethorphan 326,898
Phenylephrine 82,249
Dextromethorphan; Triprolidine 79,404
Chlorpheniramine; Dextromethorphan; Phenylephrine 69,747
Dextromethorphan; Guaifenesin 45,121
Chlorpheniramine; Phenylephrine 30,160
Brompheniramine; Dextromethorphan; Phenylephrine 28,853
Dexbrompheniramine; Dextromethorphan; Phenylephrine 19,157
Dextromethorphan; Guaifenesin; Phenylephrine (this drug) 18,373
Dextromethorphan; Phenylephrine; Pyrilamine 17,542
Dextromethorphan; Guaifenesin; Pseudoephedrine 6,963
Guaifenesin; Phenylephrine 3,269
Dextromethorphan; Phenylephrine; Triprolidine 2,319

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Actidom Dmx
  • Actinel DM
  • Actinel DM Pediatric
  • Altipres
  • Altipres Pediatric
  • Amazon
  • Bactimicina Cough And Cold
  • Biocof
  • Broncolito
  • Broncomiel
  • Childrens Cold
  • Childrens Mucinex Multi-symptom Cold
  • Childrens Mucus Cough And Congestion Relief
  • Childrens Multi Symptom Cold Very Berry
  • Childrens Multi-symptom Cold
  • Childrens Multi-symptom Cold Daytime
  • Childrens Robitussin Cough And Cold CF
  • Childrens Tussnex Multi-symptom Cold
  • Cold
  • Congestion And Cough
  • Cvs Maximum Strength Severe Congestion And Cough
  • Deconex
  • Defensol-ito
  • Desgen
  • Desgen DM
  • Fast Acting Mucus Relief
  • G-supress DX
  • G-tusicof
  • Giltuss Childrens Cough And Cold
  • Giltuss Cough And Cold
  • Giltuss TR
  • Goodsense Tussin CF Multi-symptom Cold, Raspberry
  • H E B Max Severe Congestion And Cough
  • Kroger Maximum Strength Severe Congestion And Cough
  • Leader Childrens Multi Symptom Cold
  • Maximum Strength Mucus Relief
  • Maximum Strength Mucus Relief Severe Congestion And Cough
  • Maximum Strength Severe Congestion And Cough
  • Maxium Strength Severe Congestion And Cough Max
  • Meijer Maximum Strength Severe Congestion And Cough
  • Mucinex Childrens Cough And Congestion
  • Mucinex Childrens Freefrom Multi-symptom Cold And Stuffy Nose
  • Mucinex Childrens Multi-symptom Cold
  • Mucinex Fast-max
  • Mucosan Childrens Multi-symptom Grape
  • Mucosan Multi-symptom Cherry
  • Mucosan Multi-symptom Honey
  • Mucosan Severe Multi-symptom
  • Mucus Congestion And Cough Relief
  • Mucus Relief
  • Mucus Relief Congestion And Cough
  • Mucus Relief Congestion Cough
  • Mucus Relief Severe Congestion And Cough
  • Multi-symptom Cold
  • Presgen
  • Presgen Pediatric
  • Qch Maximum Strength Mucus Relief 617
  • Robitussin Peak Cold Multi-symptom Cold
  • Rompe Pecho
  • Sanatos Turbo
  • Severe Congestion And Cough
  • Severe Congestion And Cough Max
  • Severe Congestion And Cough Relief
  • Severe Cough And Congestion
  • Signature Care
  • Stona Cough
  • Supress DX Pediatric Drops
  • Tukol A
  • Tukol Children Cough And Congestion
  • Tukol Cough And Cold Honey Flavor
  • Tukol Cough And Congestion
  • Tukol Honey Children Cough And Congestion
  • Tukol Max Action Severe Congestion And Cough
  • Tukol Multi Symptom Cold
  • Tukol X-pecto Miel
  • Tusicof
  • Tusnel
  • Tusnel Pediatric
  • Tusnel-DM Pediatric
  • Tussi Pres
  • Tussi Pres Pediatric
  • Tussin
  • Tussin CF
  • Tussin CF Multi-symptom Cold
  • Tussin Multi Symptom Cold CF
  • Tusslin
  • Tussnex FM Severe Cough And Congestion
  • UP And UP Daytime Childrens Multi Symptom Cold
  • UP And UP Maximum Strength Fast Mucus Relief
  • Vanacof DM
  • Vicks Childrens
  • Vicks Dayquil
  • Vicks Dayquil Kids
  • Vicks Dayquil Kids Berry
  • Walgreen
  • Walgreen Daytimel Kids
  • Walgreens Maximum Strength Severe Congestion And Cough
  • Winco Foods Childrens Multi Symptom Cold
Generic Drug Synonyms and Salts
  • Dextromethorphan Hydrobromide; Guaifenesin; Phenylephrine Hydrochloride
  • Dextromethorphan Hydrobromide; Phenylephrine Hydrochloride; Guaifenesin
  • Guaifenesin; Dextromethorphan Hydrobromide; Phenylephrine Hydrochloride
  • Guaifenesin; Phenylephrine Hydrochloride; Dextromethorphan Hydrobromide
  • Guaifenesin; Phenylephrine; Dextromethorphan
  • Phenylephrine Hydrochloride; Dextromethorphan Hydrobromide; Guaifenesin
  • Phenylephrine Hydrochloride; Guaifenesin; Dextromethorphan Hydrobromide
  • Dextromethorphan; Guaifenesin; Phenylephrine

FDA Approval Information

Established Pharmacologic Class (EPC): Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Initial FDA approval date: 11/24/2004
First FDA applicant: Sato Pharmaceutical Co., Ltd.
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Apr 15, 2025
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