Dextromethorphan; Guaifenesin

Drug Usage Statistics, United States, 2013 - 2021

Dextromethorphan; Guaifenesin Summary for 2021

Top drug rank #337 ( 7)
Estimated number of prescriptions in the United States (2021) 139,469
Estimated number of patients in the United States (2021) 117,473
Average total drug cost (USD)  
Per prescription $30.26
Per day of therapy $2.33/day
Average out-of-pocket cost (USD)  
Per prescription $1.86
Per day of therapy $0.08/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 391  9
2014 387  4
2015 403  16
2016 389  14
Year Rank Change
2017 393  4
2018 418  25
2019 382  36
2020 344  38
2021 337  7

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

No data available

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2021)
Guaifenesin 695,138
Dextromethorphan; Promethazine 627,117
Brompheniramine; Dextromethorphan; Pseudoephedrine 584,348
Codeine; Guaifenesin 542,423
Dextromethorphan; Guaifenesin (this drug) 139,469
Dextromethorphan 22,871
Brompheniramine; Dextromethorphan; Phenylephrine 6,055

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Guaifenesin And Dextromethorphan Hydrobromide
  • Mucinex DM
  • Basic Care Mucus DM
  • Berkley And Jensen Mucus Relief DM
  • Bisolvine
  • Breacold Adult
  • Breacold Children
  • Childrens Giltuss Honey Cough And Chest Congestion
  • Cough Mucus Relief DM
  • Defensol Adult Syrup
  • Defensolito Children Syrup
  • DG Health Mucus DM
  • Diabetic Maximum Strength Siltussin DM Das-NA
  • Diabetic Siltussin DM Das-NA
  • Dometuss-DM
  • Equaline Mucus DM
  • Exchange Select Mucus DM
  • Extra Action Cough
  • Giltuss Diabetic
  • Good Neighbor Pharmacy Mucus DM
  • Good Sense Mucus DM
  • Green Tussin
  • Guaifenesin And Dextromethorphan Oral Solution
  • Guaifenesin DM
  • Kids Cough And Chest Congestion
  • Leader Mucus DM
  • Maximum Strength Mucus DM Extended Release
  • Maximum Strength Mucus Relief DM
  • Maximum Strength Mucus-DM
  • Mediqe Medi-mucus
  • Medique Guaicon Dms
  • Mucosa DM
  • Mucus DM
  • Mucus DM Extended Release
  • Mucus Relief
  • Mucus Relief DM
  • Mucus Relief DM Expectorant And Cough Suppressant
  • Mucus Relief DM Expectorant And Cough Suppressant Maximum Strength
  • Mucus Relief DM Extended Release
  • Mucus Relief DM Extended Release Caplets
  • Mucus Relief DM Max
  • Mucus Relief DM Maximum Strength
  • Mucus Relief ER DM
  • Mucus Relief Xpect
  • Only For
  • Pharbinex-DM
  • Rabofen DM
  • Rugby Mucus Relief DM
  • Sanatos Mucus Relief Cold Toddlers
  • Siltussin DM
  • Siltussin DM Das Cough Formula
  • Sound Body Mucus DM
  • Supress DM
  • Topcare Mucus DM
  • Tukol Max Action DM Max
  • Ultra Tuss DM
  • Ultra Tuss Safe
  • UP And UP Maximum Strength Mucus Relief DM
  • Vicks
Generic Drug Synonyms and Salts
  • Dextromethorphan Hydrobromide; Guaifenesin
  • Guaifenesin; Dextromethorphan
  • Guaifenesin; Dextromethorphan Hydrobromide
  • Dextromethorphan; Guaifenesin

FDA Approval Information

Established Pharmacologic Class (EPC): Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Initial FDA approval date: 4/29/2004
First FDA applicant: Otc
First dosage form: Tablet, Extended Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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