Upper Respiratory Combinations

Multum Therapeutic Class Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Dextromethorphan; Promethazine	1,088,232	21.8%
Brompheniramine; Dextromethorphan; Pseudoephedrine	1,039,412	20.9%
Codeine; Guaifenesin	862,861	17.3%
Loratadine; Pseudoephedrine	506,937	10.2%
Dextromethorphan; Guaifenesin	487,450	9.8%
Fexofenadine; Pseudoephedrine	342,583	6.9%
Codeine; Promethazine	181,218	3.6%
Chlorpheniramine; Phenylephrine	107,375	2.2%
Dextromethorphan; Guaifenesin; Phenylephrine	54,843	1.1%
Homatropine; Hydrocodone	45,484	0.9%
Hydrocodone; Chlorpheniramine	39,773	0.8%
Dexchlorpheniramine; Dextromethorphan; Phenylephrine	36,371	0.7%
Guaifenesin; Pseudoephedrine	30,783	0.6%
Chlorpheniramine; Dextromethorphan; Phenylephrine	30,391	0.6%
Codeine; Phenylephrine; Promethazine	26,799	0.5%
Brompheniramine; Dextromethorphan; Phenylephrine	19,849	0.4%
Dexbrompheniramine; Dextromethorphan; Phenylephrine	17,778	0.4%
Dextromethorphan; Pheniramine; Phenylephrine	16,261	0.3%
Pseudoephedrine; Triprolidine	13,177	0.3%
Chlorcyclizine; Pseudoephedrine	10,928	0.2%
Cetirizine; Pseudoephedrine	9,084	0.2%
Dexbrompheniramine; Phenylephrine	7,498	0.2%
Brompheniramine; Phenylephrine	6,062	0.1%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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