Drug Usage Statistics, United States, 2013 - 2021

Dextromethorphan Summary for 2021

Top drug rank #380 ( 54)
Estimated number of prescriptions in the United States (2021) 22,871
Estimated number of patients in the United States (2021) 9,081
Average total drug cost (USD)  
Per prescription $6.27
Per day of therapy $0.00/day
Average out-of-pocket cost (USD)  
Per prescription $4.54
Per day of therapy $0.00/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 435  122
2014 444  9
2015 459  15
2016 449  10
Year Rank Change
2017 451  2
2018 413  38
2020 434 -
2021 380  54

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

Dosage Form Strength % of Dispensed Products
Suspension 30/5 mg/ml 100.0%

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Delsym
  • Adult Cough Relief DM
  • Adult Wal Tussin
  • Basic Care Childrens Cough DM
  • Basic Care Cough DM
  • Cabinet Cough Relief
  • Careone Cough DM
  • Careone Tussin
  • Childrens Cough DM
  • Childrens Giltuss Honey DM Cough
  • Childrens Robitussin 12 Hour Cough Relief
  • Childrens Robitussin Cough Long-acting
  • Cough Control
  • Cough DM
  • Cough Gels
  • Cough Medicine
  • Cough Relief
  • Creomulsion
  • Daytime Cough
  • Delsym Cough
  • Dextromethorphan Hbr 15 MG
  • Dextromethorphan Polistirex Extended Release
  • Dextromethorphan Polistirex Extended-release
  • DG Health Cough DM
  • Equaline Cough DM
  • Equaline Tussin Cough
  • Equate Cough DM
  • Father Johns Medicine
  • Giltuss Honey DM Cough
  • Good Neighbor Pharmacy Cough DM ER
  • Good Neighbor Pharmacy Tussin
  • Good Sense Cough DM
  • Harris Teeter Cough DM
  • Health Mart Cough DM
  • Honey Works
  • Leader Childrens Cough DM
  • Leader Cough
  • Leader Cough DM
  • Long Acting Cough Softgels
  • Mielim Y Mas
  • Mixed Berry Sore Throat And Cough Lozenge
  • Premier Value Tussin Cough
  • Robafen Cough
  • Robitussin 12 Hour Cough Relief
  • Robitussin Lingering Cold Long-acting Coughgels
  • Robitussin Long-acting Coughgels
  • Robo Cough
  • Scot-tussin Diabetes Cough Formula With DM
  • Signature Care 12 Hour Cough Relief
  • Signature Care Cough Relief
  • Signature Care Daytime Cough
  • Silphen DM Cough
  • Stona
  • Sunmark Cough DM
  • Topcare Cough DM
  • Topcare Tussin
  • Tussin
  • Tussin Cough
  • Tussin Cough Gels
  • Tussin Long Acting Cough
  • UP And UP 12 Hour Cough Relief
  • Vanacof Dmx
  • Vicks
  • Vicks Dayquil
  • Wal-tussin
Generic Drug Synonyms and Salts
  • Dextromethorphan Hydrobromide
  • Dextromethorphan Polistirex
  • Dextromethorphan

FDA Approval Information

Established Pharmacologic Class (EPC): Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Initial FDA approval date: 10/8/1982
First FDA applicant: Otc
First dosage form: Suspension, Extended Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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