Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Established Pharmacologic Class (EPC) Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name Total Prescriptions (2022) Percent Share
Dextromethorphan; Promethazine 1,088,232 36.9%
Brompheniramine; Dextromethorphan; Pseudoephedrine 1,039,412 35.3%
Dextromethorphan; Guaifenesin 487,450 16.5%
Dextromethorphan 158,061 5.4%
Dextromethorphan; Guaifenesin; Phenylephrine 54,843 1.9%
Dexchlorpheniramine; Dextromethorphan; Phenylephrine 36,371 1.2%
Chlorpheniramine; Dextromethorphan; Phenylephrine 30,391 1%
Brompheniramine; Dextromethorphan; Phenylephrine 19,849 0.7%
Dexbrompheniramine; Dextromethorphan; Phenylephrine 17,778 0.6%
Dextromethorphan; Pheniramine; Phenylephrine 16,261 0.6%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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