Brompheniramine; Dextromethorphan; Pseudoephedrine

Drug Usage Statistics, United States, 2013 - 2021

Brompheniramine; Dextromethorphan; Pseudoephedrine Summary for 2021

Top drug rank #294 ( 65)
Estimated number of prescriptions in the United States (2021) 584,348
Estimated number of patients in the United States (2021) 525,735
Average total drug cost (USD)  
Per prescription $22.34
Per day of therapy $6.88/day
Average out-of-pocket cost (USD)  
Per prescription $6.83
Per day of therapy $3.98/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 359  23
2014 340  19
2015 332  8
2016 343  11
Year Rank Change
2017 336  7
2018 304  32
2019 286  18
2020 359  73
2021 294  65

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

No data available

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2021)
Brimonidine 3,470,856
Epinephrine 1,896,954
Fexofenadine; Pseudoephedrine 829,016
Dextromethorphan; Promethazine 627,117
Brompheniramine; Dextromethorphan; Pseudoephedrine (this drug) 584,348
Loratadine; Pseudoephedrine 362,280
Pseudoephedrine 295,652
Dextromethorphan; Guaifenesin 139,469
Pseudoephedrine; Triprolidine 102,352
Cetirizine; Pseudoephedrine 66,267
Dextromethorphan 22,871
Brompheniramine; Dextromethorphan; Phenylephrine 6,055
Guaifenesin; Pseudoephedrine 5,925
Pseudoephedrine; Codeine; Guaifenesin 2,532

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Bromanate DM
  • Bromfed-DM
  • Brompheniramine Maleate, Pseudoephedrine Hydrochloride And Dextromethorphan Hydrobromide
  • Dimetane-DX
  • Bromfed DM
  • Brompheniramine Maleate, Pseudoephedrine Hydrochloride And Dextromethorphanhydrobromide
  • Brompheniramine Maleate, Pseudoephedrine Hydrochloride, And Dextromethorphan Hydrobromide
  • Brompheniramine Maleate, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide
  • Brotapp DM Cold And Cough
Generic Drug Synonyms and Salts
  • Brompheniramine Maleate; Dextromethorphan Hydrobromide; Pseudoephedrine Hydrochloride
  • Brompheniramine Maleate; Pseudoephedrine Hydrochloride; Dextromethorphan Hydrobromide
  • Dextromethorphan Hydrobromide; Pseudoephedrine Hydrochloride; Brompheniramine Maleate
  • Pseudoephedrine Hydrochloride; Brompheniramine Maleate; Dextromethorphan Hydrobromide
  • Brompheniramine; Dextromethorphan; Pseudoephedrine

FDA Approval Information

Established Pharmacologic Class (EPC): Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist, alpha-Adrenergic Agonist
Initial FDA approval date: 8/24/1984
First FDA applicant: Discn
First dosage form: Syrup (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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