Metabolic Agents

Multum Therapeutic Class Comparison, United States, 2023

Total Prescriptions in (2023)

Drug Name	Total Prescriptions (2023)	Percent Share
Atorvastatin	115,271,515	24.3%
Metformin	85,685,926	18%
Rosuvastatin	42,103,430	8.9%
Semaglutide	25,954,067	5.5%
Simvastatin	24,585,762	5.2%
Insulin Glargine	18,424,802	3.9%
Empagliflozin	16,744,582	3.5%
Glipizide	15,173,476	3.2%
Allopurinol	14,311,840	3%
Pravastatin	11,060,711	2.3%
Dulaglutide	10,358,270	2.2%
Ezetimibe	9,686,244	2%
Glimepiride	8,459,351	1.8%
Fenofibrate	8,093,231	1.7%
Insulin Lispro	8,053,452	1.7%
Dapagliflozin	7,444,832	1.6%
Insulin Aspart	6,835,070	1.4%
Tirzepatide	6,310,174	1.3%
Alendronate	5,876,378	1.2%
Sitagliptin	5,171,310	1.1%
Lovastatin	4,392,660	0.9%
Pioglitazone	4,381,831	0.9%
Insulin Degludec	3,663,826	0.8%
Insulin Detemir	3,584,061	0.8%
Insulin Human; Insulin Isophane Human	3,487,065	0.7%
Evolocumab	2,633,257	0.6%
Liraglutide	2,191,691	0.5%
Colchicine	2,010,102	0.4%
Icosapent Ethyl	1,378,689	0.3%
Linagliptin	1,158,877	0.2%
Niacin	534,979	0.1%
Glucose	4,481	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2023. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2025.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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