Metabolic Agents

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name Total Prescriptions (2020) Percent Share
Atorvastatin 114,509,815 24.3%
Metformin 92,591,486 19.6%
Simvastatin 36,600,871 7.8%
Rosuvastatin 29,750,488 6.3%
Insulin Glargine 17,973,209 3.8%
Pravastatin 17,549,151 3.7%
Allopurinol 15,303,283 3.2%
Glipizide 13,674,143 2.9%
Insulin Lispro 10,013,738 2.1%
Sitagliptin 9,885,657 2.1%
Insulin Aspart 9,124,642 1.9%
Glimepiride 8,566,883 1.8%
Alendronate 7,923,120 1.7%
Fenofibrate 7,668,856 1.6%
Dulaglutide 7,657,320 1.6%
Lovastatin 7,033,635 1.5%
Ezetimibe 7,029,303 1.5%
Empagliflozin 6,724,609 1.4%
Insulin Detemir 5,164,647 1.1%
Semaglutide 4,827,484 1%
Insulin Degludec 4,600,262 1%
Liraglutide 4,063,184 0.9%
Metformin; Sitagliptin 3,847,463 0.8%
Pioglitazone 3,443,215 0.7%
Gemfibrozil 2,679,954 0.6%
Glyburide 2,417,883 0.5%
Dapagliflozin 2,233,919 0.5%
Insulin Isophane 2,171,842 0.5%
Empagliflozin; Metformin 1,891,720 0.4%
Colchicine 1,876,591 0.4%
Insulin Human; Insulin Isophane Human 1,755,906 0.4%
Icosapent Ethyl 1,238,695 0.3%
Linagliptin 1,168,074 0.2%
Canagliflozin 1,143,266 0.2%
Alogliptin 1,141,082 0.2%
Ibandronate 1,036,005 0.2%
Insulin, Regular, Human 1,012,100 0.2%
Evolocumab 979,183 0.2%
Insulin Aspart Protamine, Human 978,431 0.2%
Ertugliflozin 830,300 0.2%
Niacin 810,390 0.2%
Pitavastatin 763,332 0.2%
Insulin Aspart Protamine, Human; Insulin Aspart, Human 120,285 0%
Glucose 110,886 0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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