Digoxin Calculator for Heart Failure and Atrial Fibrillation

Digoxin calculator to determine the optimal maintenance dose of digoxin for both heart failure and atrial fibrillation patients, based on the Bauman-DiDomenico and Koup-Jusko methods.
Keywords: digoxin, heart, failure, atrial, fibrillation, tachycardia, arrhythmia, rate, control, DIG, HFSA, empiric, bauman, didomenico, nomogram, jelliffe, koup, jusko, digitalis, maintenance, steady state, trough, concentration, PROVED, RADIANCE

Aminoglycoside Calculator

Advanced aminoglycoside pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods to determine an optimal gentamicin, tobramycin, or amikacin dose.
Keywords: aminoglycoside, AMG, gentamicin, tobramycin, amikacin, pharmacokinetic, equations, trough, peak, extended-interval, conventional, Hartford, Barnes-Jewish, Rochester, Urban-Craig, levels

Vancomycin Calculator

Advanced vancomycin pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods, including Bayesian modeling, to determine the optimal vancomycin dose.
Keywords: vancomycin, bayesian, pharmacokinetic, equations, vancocin, MIC, AUC:MIC, MRSA, guidelines, trough, peak, AUC, vanc, vanco

Corticosteroid Conversion Calculator

Online calculator to convert equivalent doses of corticosteroid compounds.
Keywords: corticosteroid, glucocorticoid, mineralocorticoid, converter, conversion, equivalence, equivalent, calculator, potency, equipotent, anti-inflammatory, cortisone, hydrocortisone, prednisone, prednisolone, triamcinolone, methylprednisolone, betamethasone, dexamethasone, fludrocortisone

Phenytoin (Dilantin) Correction Calculator

Total phenytoin correction calculator converts a measured total phenytoin level to a corrected total and estimated free level. This calculator accounts for renal dysfunction, serum albumin level, age, and comorbidities.
Keywords: phenytoin, dilantin, winter-tozer, winter, tozer, sheiner, correction, corrected, albumin, renal, free, total, unbound, equation, calculator, hypoalbuminemia, uremia, trauma, head trauma, PHT

Total Parenteral Nutrition (TPN) Macronutrient Calculator

Total parenteral nutrition (TPN) calculator to determine a patient's macronutrient requirements (dextrose, protein, and lipids)
Keywords: TPN, total, parenteral, nutrition, PPN, dextrose, protein, lipid, intralipid, nutritional, GIR, glucose, infusion, rate, osmolarity, macronutrient

Glucose Infusion Rate Calculator

GIR (glucose infusion rate) calculator for total parenteral nutrition (TPN)
Keywords: GIR, glucose, infusion, rate, TPN, total, parenteral, nutrition, overfeeding, underfeeding, dextrose

Opioid Equianalgesic Calculator

Online calculator to convert equianalgesic doses of opioid narcotic analgesics.
Keywords: opioid, opiate, narcotic, analgesic, conversion, converter, calculator, equianalgesic, equianalgesia, equivalent, equivalence, potency, equipotent, American Pain Society, pain, cross-tolerance

Sample Size Calculator

Calculator to determine the minimum number of subjects to enroll in a study for adequate power.
Keywords: sample, size, statistical, power, alpha, beta, 0.05, type 1, type 2, type I, type II, calculator, equations, mean, incidence, binomial, continuous

Post-hoc Power Calculator

Calculator to determine the post-hoc power of an existing study.
Keywords: post-hoc, analysis, sample, size, statistical, power, alpha, beta, 0.05, type 1, type 2, type I, type II, calculator, equations, mean, incidence, binomial, continuous

Printable Aminoglycoside Nomograms

Printable extended-interval aminoglycoside nomograms.
Keywords: aminoglycoside, AMG, gentamicin, tobramycin, amikacin, extended-interval, Hartford, Barnes-Jewish, Rochester, Urban-Craig, extended, high dose

HAS-BLED Calculator for Atrial Fibrillation

HAS-BLED calculator for evaluating major bleeding risk in patients with atrial fibrillation.
Keywords: HAS-BLED, HASBLED, HAD-BLED, HADBLED, HEMORRHAGES, Pisters Lip, atrial, fibrillation, afib, AF, bleeding, hemorrhage, risk, per year

Enteral Nutrition Calculator

Calculator to estimate enteral nutrition (tube feeding) needs in adults patients.
Keywords: enteral, nutrition, tube, feeds, feeding, caloric, calorie, requirements, needs, ASPEN, ESPEN, calculator, calc, jevity, osmolite, nutren, glucerna, nepro, impact, oxepa, nutren, peptamen, replete

ICU Trials by ClinCalc

Summarized landmark critical care trials -- right at your fingertips!
Keywords: icu, critical, care, intensive care, critical care, landmark, pivotal, evidence-based medicine, literature, seminal, reference, trials, summary, top

Odds Ratio to Risk Ratio Conversion

Tool to convert OR (odds ratio) to RR (risk ratio) from logistic regression.
Keywords: or, rr, odds ratio, risk ratio, relative risk, cohort, convert, converter, conversion, logistic, regression

Enteral and Parenteral Nutrition Summary

Calculator to analyze a patient's enteral and parenteral nutrition intake, including calories, dextrose, protein, and lipids.
Keywords: TPN, total parenteral nutrition, dextrose, protein, lipid, intralipid, nutritional, GIR, glucose, infusion, rate, macronutrient, enteral, nutrition, tube, feeds, feeding, caloric, calorie, kcal, requirements, needs, ASPEN, ESPEN, calculator

Benzodiazepine Equivalence Calculator

Conversion tool to calculate benzodiazepine equivalents (convert equivalent benzodiazepine doses).
Keywords: benzo, benzodiazepine, bzd, convert, conversion, converter, calculator, equivalent, equivalents, equivalence, potency, equipotent, diazepam, lorazepam, alprazolam, midazolam, phenobarbital

Interactive Visualization Tool for 10-Year ASCVD Risk

Visually analyze the 10-year ACC/AHA atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equations using 2D and 3D graphing techniques.
Keywords: ascvd, acc/aha, pooled cohort equation, pooled cohort equations, atherosclerotic, cardiovascular, disease, risk, 10-year, 10 year, visualize, graph, graphically, visual, 3D, analyze

Colistin Calculator

Advanced parenteral colistin (colistimethate sodium - CMS) pharmacokinetic and calculation tool. Utilizes the most updated, evidence-based literature for a variety of challenging patient populations.
Keywords: colistin, colistimethate, CBA, colistin base activity, Coly-Mycin, pharmacokinetic, equations, dosing, dose, calc, calculator, calculation, tool

Eight Quick Tips on Inferring Antibiotic Susceptibility Results

Antibiotic susceptibility testing is commonly used to select appropriate antimicrobial therapy or deescalate to a narrower spectrum agent.  Because not every antibiotic is tested, clinicians must infer certain types of antibiotic susceptibility based on bacterial patterns of resistance and sensitivities of other antibiotics. The following are 8 quick tips regarding inferred antibiotic susceptibility, which are […]

Opioid Conversion Calculator – Now Available

Converting between equianalgesic opioid dosing isn’t exactly a hard science.  Given the lack of blinded trials, bidirectional conversions, dose-dependent conversions, incomplete cross-tolerance, equianalgesic discrepancies in the literature, and patient-specific factors (specifically metabolism and absorption), a “simple” equianalgesic conversion table often doesn’t do the process justice.

WARFASA Trial – Aspirin for VTE Prophylaxis

The WARFASA trial, recently published in the NEJM, examined the role of aspirin after patients with VTE’s had completed 6-18 months of warfarin therapy.  Given the safety of the treatment and the impressive reduction in VTE recurrence, it’s very likely that the results of the  WARFASA trial will find their way into the next CHEST guideline updates.

Freshly Baked Vancomycin iPhone App!

Update March 29, 2014: Vancomycin Calculator for Android and iPhone had received a significant upgrade in both user interface and functionality.  Due to developer time and cost, the lite version has been removed from both markets and the paid version price has increased to $2.99.  See all the features of the mobile Vancomycin Calculator by […]

Aminoglycoside Calculator – Now Available!

Aminoglycosides have a narrow therapeutic window necessitating therapeutic drug monitoring for safe and effective use.  Either fortunately or unfortunately, their use has fallen out of favor and many clinicians are now less familiar with dosing these agents.  Combining unfamiliarity with complex pharmacokinetic calculations, the risk of medication errors with aminoglycosides is extremely high.  For these […]

Vancomycin AUC:MIC versus T>MIC

There is a significant amount of controversy regarding the most appropriate therapeutic goal for vancomycin therapy. The difference of opinion stems from the pharmacodynamic activity of vancomycin. Definitions MIC (minimum inhibitory concentration) – The minimum concentration of antibiotic to inhibit the growth of an organism. AUC (area under the curve) – The total exposure of […]

Ideal Body Weight Calculator – Now Available!

Ideal body weight and other body weight measures are widely used for a variety of medical purposes, including drug dosing, renal function, categorizing obesity, and dosing chemotherapy.  The newest ClinCalc, the Ideal Body Weight Calculator, is capable of providing results and equations for the following body weight metrics: Ideal body weight (based on the Devine 1974 […]

Top 10 Facts about Creatinine Clearance … and a New ClinCalc

Evaluating renal function for the purposes of drug dosing is a common task for clinical pharmacists, but a number of misconceptions have developed over the past forty years as the process of evaluating renal function has improved.  The following are the top 10 facts that every clinician should know about creatinine clearance: Cockcroft-Gault is still […]

The Evidence behind Continuous-Infusion Vancomycin Therapy

Vancomycin is typically given as an intermittent infusion adjusted for body weight and renal function.  Some clinicians believe that a continuous infusion of vancomycin may simplify therapy and make serum vancomycin levels more consistent. Goal Vancomycin Level (Plateau) Because continuous infusion vancomycin is a rare clinical occurrence, there is a lack of data regarding the […]