Digoxin calculator to determine the optimal maintenance dose of digoxin for both heart failure and atrial fibrillation patients, based on the Bauman-DiDomenico and Koup-Jusko methods.
Advanced aminoglycoside pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods to determine an optimal gentamicin, tobramycin, or amikacin dose.
Advanced vancomycin pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods, including Bayesian modeling, to determine the optimal vancomycin dose.
Total phenytoin correction calculator converts a measured total phenytoin level to a corrected total and estimated free level. This calculator accounts for renal dysfunction, serum albumin level, age, and comorbidities.
Advanced parenteral colistin (colistimethate sodium - CMS) pharmacokinetic and calculation tool. Utilizes the most updated, evidence-based literature for a variety of challenging patient populations.
Ready to improve your ICU knowledge? Check out ICU Trials for iPhone and Android, a pocket reference for 70+ landmark critical care trials, including Wunderink 2012. Summary of the Wunderink 2012 Trial In a cohort of patients with MRSA pneumonia, linezolid was shown to improve clinical cure rate and cause less nephrotoxicity than vancomycin, but […]
Ready to improve your ICU knowledge? Check out ICU Trials for iPhone and Android, a pocket reference for 70+ landmark critical care trials, including HACA. Summary of the HACA Trial Therapeutic hypothermia improved 6-month neurologic outcome and mortality among patients with out-of-hospital VT/VF cardiac arrest. Note that hypothermia may be associated with certain complications, such […]
Ready to improve your ICU knowledge? Check out ICU Trials for iPhone and Android, a pocket reference for 70+ landmark critical care trials, including CRASH 2. Summary of the CRASH 2 Trial Tranexamic acid reduced all-cause mortality in a broad population of trauma patients without an increase in vascular occlusion complications.
We’ve been very busy over the past few months to release a brand new, fully upgraded version of ClinCalc.com. Today, these updates are now available! Read below for the major updates that we’ve released, but rest assured, there are many, many more under-the-hood updates for nearly all of the 25+ clinical calculators on ClinCalc.
There’s nothing that smells sweeter than a freshly based mobile app for medical education. Our newest app, FlashRX by ClinCalc, is no exception! As a professor, I commonly see frustrated students with complicated drug cards that provide excessive, non-prioritized information. Instead of these complicated drug cards, FlashRX’s drug database focuses on simple, usable information to develop […]
Recommend taking at least one antihypertensive medication at night. This simple, cost-effective intervention was recently shown in the MAPEC trial to modestly reduce cardiovascular events and mortality.
As it turns out, patients with ARDS should be belly sleepers. The PROSEVA trial, freshly published in NEJM, examined the role of prone positioning in patients with early, severe acute respiratory distress syndrome (ARDS).
Voluven (hydroxyethyl starch 130/0.4) was heralded to the hospital community as a cheaper alternative to albumin, but safer than previous hydroxyethyl starch (HES) products that were shown to cause bleeding and renal failure. Although Voluven is likely “safer” than older HES products, it still is NOT safer than traditional volume repletion with normal saline or […]
Magnesium repletion is very common in hospitalized patients. Is there any difference between PO and IV magnesium in patients without symptoms of hypomagnesemia?
Amlodipine (Norvasc) is a great drug — but it takes 8 hours for the drug to reach its peak drug concentration, and about a week to reach steady-state full antihypertensive effect.
Kane SP. Search Results ter Page 4. ClinCalc: https://clincalc.com/blog/2013/03/using-amlodipine-responsibly-in-hospitalized-patients/. Updated September 9, 2014. Accessed May 24, 2022.