Digoxin Calculator for Heart Failure and Atrial Fibrillation

Digoxin calculator to determine the optimal maintenance dose of digoxin for both heart failure and atrial fibrillation patients, based on the Bauman-DiDomenico and Koup-Jusko methods.
Keywords: digoxin, heart, failure, atrial, fibrillation, tachycardia, arrhythmia, rate, control, DIG, HFSA, empiric, bauman, didomenico, nomogram, jelliffe, koup, jusko, digitalis, maintenance, steady state, trough, concentration, PROVED, RADIANCE

Aminoglycoside Calculator

Advanced aminoglycoside pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods to determine an optimal gentamicin, tobramycin, or amikacin dose.
Keywords: aminoglycoside, AMG, gentamicin, tobramycin, amikacin, pharmacokinetic, equations, trough, peak, extended-interval, conventional, Hartford, Barnes-Jewish, Rochester, Urban-Craig, levels

Vancomycin Calculator

Advanced vancomycin pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods, including Bayesian modeling, to determine the optimal vancomycin dose.
Keywords: vancomycin, bayesian, pharmacokinetic, equations, vancocin, MIC, AUC:MIC, MRSA, guidelines, trough, peak, AUC, vanc, vanco

Corticosteroid Conversion Calculator

Online calculator to convert equivalent doses of corticosteroid compounds.
Keywords: corticosteroid, glucocorticoid, mineralocorticoid, converter, conversion, equivalence, equivalent, calculator, potency, equipotent, anti-inflammatory, cortisone, hydrocortisone, prednisone, prednisolone, triamcinolone, methylprednisolone, betamethasone, dexamethasone, fludrocortisone

Phenytoin (Dilantin) Correction Calculator

Total phenytoin correction calculator converts a measured total phenytoin level to a corrected total and estimated free level. This calculator accounts for renal dysfunction, serum albumin level, age, and comorbidities.
Keywords: phenytoin, dilantin, winter-tozer, winter, tozer, sheiner, correction, corrected, albumin, renal, free, total, unbound, equation, calculator, hypoalbuminemia, uremia, trauma, head trauma, PHT

Total Parenteral Nutrition (TPN) Macronutrient Calculator

Total parenteral nutrition (TPN) calculator to determine a patient's macronutrient requirements (dextrose, protein, and lipids)
Keywords: TPN, total, parenteral, nutrition, PPN, dextrose, protein, lipid, intralipid, nutritional, GIR, glucose, infusion, rate, osmolarity, macronutrient

Glucose Infusion Rate Calculator

GIR (glucose infusion rate) calculator for total parenteral nutrition (TPN)
Keywords: GIR, glucose, infusion, rate, TPN, total, parenteral, nutrition, overfeeding, underfeeding, dextrose

Opioid Equianalgesic Calculator

Online calculator to convert equianalgesic doses of opioid narcotic analgesics.
Keywords: opioid, opiate, narcotic, analgesic, conversion, converter, calculator, equianalgesic, equianalgesia, equivalent, equivalence, potency, equipotent, American Pain Society, pain, cross-tolerance

Sample Size Calculator

Calculator to determine the minimum number of subjects to enroll in a study for adequate power.
Keywords: sample, size, statistical, power, alpha, beta, 0.05, type 1, type 2, type I, type II, calculator, equations, mean, incidence, binomial, continuous

Post-hoc Power Calculator

Calculator to determine the post-hoc power of an existing study.
Keywords: post-hoc, analysis, sample, size, statistical, power, alpha, beta, 0.05, type 1, type 2, type I, type II, calculator, equations, mean, incidence, binomial, continuous

Printable Aminoglycoside Nomograms

Printable extended-interval aminoglycoside nomograms.
Keywords: aminoglycoside, AMG, gentamicin, tobramycin, amikacin, extended-interval, Hartford, Barnes-Jewish, Rochester, Urban-Craig, extended, high dose

HAS-BLED Calculator for Atrial Fibrillation

HAS-BLED calculator for evaluating major bleeding risk in patients with atrial fibrillation.
Keywords: HAS-BLED, HASBLED, HAD-BLED, HADBLED, HEMORRHAGES, Pisters Lip, atrial, fibrillation, afib, AF, bleeding, hemorrhage, risk, per year

Enteral Nutrition Calculator

Calculator to estimate enteral nutrition (tube feeding) needs in adults patients.
Keywords: enteral, nutrition, tube, feeds, feeding, caloric, calorie, requirements, needs, ASPEN, ESPEN, calculator, calc, jevity, osmolite, nutren, glucerna, nepro, impact, oxepa, nutren, peptamen, replete

ICU Trials by ClinCalc

Summarized landmark critical care trials -- right at your fingertips!
Keywords: icu, critical, care, intensive care, critical care, landmark, pivotal, evidence-based medicine, literature, seminal, reference, trials, summary, top

Odds Ratio to Risk Ratio Conversion

Tool to convert OR (odds ratio) to RR (risk ratio) from logistic regression.
Keywords: or, rr, odds ratio, risk ratio, relative risk, cohort, convert, converter, conversion, logistic, regression

Enteral and Parenteral Nutrition Summary

Calculator to analyze a patient's enteral and parenteral nutrition intake, including calories, dextrose, protein, and lipids.
Keywords: TPN, total parenteral nutrition, dextrose, protein, lipid, intralipid, nutritional, GIR, glucose, infusion, rate, macronutrient, enteral, nutrition, tube, feeds, feeding, caloric, calorie, kcal, requirements, needs, ASPEN, ESPEN, calculator

Benzodiazepine Equivalence Calculator

Conversion tool to calculate benzodiazepine equivalents (convert equivalent benzodiazepine doses).
Keywords: benzo, benzodiazepine, bzd, convert, conversion, converter, calculator, equivalent, equivalents, equivalence, potency, equipotent, diazepam, lorazepam, alprazolam, midazolam, phenobarbital

Interactive Visualization Tool for 10-Year ASCVD Risk

Visually analyze the 10-year ACC/AHA atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equations using 2D and 3D graphing techniques.
Keywords: ascvd, acc/aha, pooled cohort equation, pooled cohort equations, atherosclerotic, cardiovascular, disease, risk, 10-year, 10 year, visualize, graph, graphically, visual, 3D, analyze

Colistin Calculator

Advanced parenteral colistin (colistimethate sodium - CMS) pharmacokinetic and calculation tool. Utilizes the most updated, evidence-based literature for a variety of challenging patient populations.
Keywords: colistin, colistimethate, CBA, colistin base activity, Coly-Mycin, pharmacokinetic, equations, dosing, dose, calc, calculator, calculation, tool

Apixaban Should Be the Preferred DOAC for Venous Thromboembolism and Nonvalvular Atrial Fibrillation

In the United States, there are currently four direct oral anticoagulants (DOACs).  All four DOACs are approved for the treatment of venous thromboembolism (VTE) and nonvalvular atrial fibrillation (NVAF), among other indications.1-4  Despite differences in pharmacology, pharmacokinetics, and clinical trial efficacy and safety data, current guidelines do not prefer a specific DOAC.  Given the lack […]

Calculate a “Fragility Index” to see which clinical trials BARELY meet statistical significance

ClinCalc.com's Fragility Index Calculator

When evaluating a clinical trial, readers often jump to the P value of the primary endpoint to determine whether the results of a trial are “statistically significant” or not. Although the P value is truly a continuous variable, the scientific community has been conditioned to disregard all results with P values ≥ 0.05, but to […]

How to Convert from IDMS to Non-IDMS Serum Creatinine Values

Historically, serum creatinine was analyzed from a blood sample using a method called alkaline picrate.  In addition to creatinine molecules, though, it also “counted” non-creatinine molecules that falsely elevated the resulting value by as much as 20%.  This assay method was used for decades in the development of creatinine clearance estimates, such as the Cockcroft-Gault method. Within […]

New Colistin (colistimethate sodium) Calculator

Pseudomonas aeruginosa nutrient agar

Colistin (in the form of colistimethate sodium, or CMS, in the United States) is an older, last-line agent for multidrug-resistant gram-negative infections.  Because of colistin’s complex pharmacokinetics and for historical reasons, there is a paucity of data regarding its dosing in patients with severe gram negative infections, particularly for those with concurrent renal dysfunction. In one of […]

It’s Time to Say “Goodbye” to Vitamin D2 (ergocalciferol)

Prescription bottle of ergocalciferol (Vitamin D2) 50,000 IU

In the United States, vitamin D supplementation is primarily available as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Although these two have historically been considered interchangeable and equipotent, the current body of literature strongly supports the preference of Vitamin D3 (cholecalciferol) over D2 (ergocalciferol). Vitamin D2 versus Vitamin D3 Vitamin D3 (cholecalciferol) is produced by […]

Vancomycin Calculator Update – End of Infusion Peak (EoIP)

We’re releasing a major update to the calculation for our popular vancomycin calculator today. Briefly, the new update implements more advanced calculations when adjusting a vancomycin dose based on a trough level. Drug Elimination during Vancomycin Infusion When adjusting vancomycin based on a trough level, pharmacokinetic textbooks recommend estimating a vancomycin peak level using the […]

ICU Trials Passes 100 Landmark Studies

Summarized landmark critical care trials on your mobile device

ClinCalc.com is proud to announce that ICU Trials by ClinCalc, a mobile application that summarizes landmark critical care trials, has surpassed 100 studies in the app database! With our most recent update on April 18th, the following recent and historic landmark trials were added: MIDEX (2012): Dexmedetomidine vs. midazolam for mechanical ventilation PAC-Man (2005): Efficacy […]

Speed Up Video Playback of The Top 250 Drugs Online Course

Increase Vimeo playback speed (Chrome extension)

At ClinCalc.com, we’re huge fans of listening and watching educational content at a faster than normal pace. Unfortunately, the video provider used for The Top 250 Drugs (online drug therapy course) does not allow for the ability to change playback speed. If you’re using Google Chrome or Mozilla Firefox, though, you’re in luck!  Both web browsers […]

The Top 250 Drugs – Online Pharmacotherapy Video Course

ClinCalc DrugStats Database

ClinCalc.com has been a bit quiet over the past year.  Our Twitter account has been mute, email updates rare, and website updates sparse. Why the radio silence? We’ve been diligently working on an exciting new product for the past year.  Quite literally, HUNDREDS of hours have been poured into the conception, creation, and implementation of this amazing new product. […]

Really NEJM? Shocking Failure of the Peer Review Process for the ALBIOS Trial

Three nuts waiting to be cracked

The New England Journal of Medicine released three landmark trials this week.  Each trial directly addresses controversies in sepsis management that have been debated for a decade or longer: high versus low MAP goals (SEPSISPAM), a challenge to early goal-directed therapy (ProCESS), and albumin replacement (ALBIOS). These trials will undoubtedly have a significant impact on […]