It’s Time to Say “Goodbye” to Vitamin D2 (ergocalciferol)

Prescription bottle of ergocalciferol (Vitamin D2) 50,000 IU

In the United States, vitamin D supplementation is primarily available as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Although these two have historically been considered interchangeable and equipotent, the current body of literature strongly supports the preference of Vitamin D3 (cholecalciferol) over D2 (ergocalciferol). Vitamin D2 versus Vitamin D3 Vitamin D3 (cholecalciferol) is produced by […]

Vancomycin Calculator Update – End of Infusion Peak (EoIP)

We’re releasing a major update to the calculation for our popular vancomycin calculator today. Briefly, the new update implements more advanced calculations when adjusting a vancomycin dose based on a trough level. Drug Elimination during Vancomycin Infusion When adjusting vancomycin based on a trough level, pharmacokinetic textbooks recommend estimating a vancomycin peak level using the […]

ICU Trials Passes 100 Landmark Studies

Summarized landmark critical care trials on your mobile device

ClinCalc.com is proud to announce that ICU Trials by ClinCalc, a mobile application that summarizes landmark critical care trials, has surpassed 100 studies in the app database! With our most recent update on April 18th, the following recent and historic landmark trials were added: MIDEX (2012): Dexmedetomidine vs. midazolam for mechanical ventilation PAC-Man (2005): Efficacy […]

Speed Up Video Playback of The Top 250 Drugs Online Course

Increase Vimeo playback speed (Chrome extension)

At ClinCalc.com, we’re huge fans of listening and watching educational content at a faster than normal pace. Unfortunately, the video provider used for The Top 250 Drugs (online drug therapy course) does not allow for the ability to change playback speed. If you’re using Google Chrome or Mozilla Firefox, though, you’re in luck!  Both web browsers […]

The Top 250 Drugs – Online Pharmacotherapy Video Course

ClinCalc DrugStats Database

ClinCalc.com has been a bit quiet over the past year.  Our Twitter account has been mute, email updates rare, and website updates sparse. Why the radio silence? We’ve been diligently working on an exciting new product for the past year.  Quite literally, HUNDREDS of hours have been poured into the conception, creation, and implementation of this amazing new product. […]

Really NEJM? Shocking Failure of the Peer Review Process for the ALBIOS Trial

Three nuts waiting to be cracked

The New England Journal of Medicine released three landmark trials this week.  Each trial directly addresses controversies in sepsis management that have been debated for a decade or longer: high versus low MAP goals (SEPSISPAM), a challenge to early goal-directed therapy (ProCESS), and albumin replacement (ALBIOS). These trials will undoubtedly have a significant impact on […]

New Web-Based 10-Year ASCVD Risk Calculator (Pooled Cohort Equations)

ASCVD Calculator for Android and iOS

    At ClinCalc, we’re very proud to announce the availability of both a web-based 10-year ASCVD Risk Calculator (also termed the Pooled Cohort Equations Calculator).  This risk assessment tool is recommended by the newly published 2013 ACC/AHA cholesterol guidelines to estimate 10-year risk of atherosclerotic cardiovascular disease (ASCVD).