Topical Agents

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name Total Prescriptions (2020) Percent Share
Fluticasone 24,777,490 16.3%
Estradiol 11,307,656 7.4%
Diclofenac 9,926,750 6.5%
Latanoprost 9,722,631 6.4%
Triamcinolone 6,422,562 4.2%
Clindamycin 5,131,000 3.4%
Timolol 4,295,413 2.8%
Hydrocortisone 3,998,412 2.6%
Prednisolone 3,894,469 2.6%
Bimatoprost 3,483,064 2.3%
Ketoconazole 3,417,349 2.3%
Clobetasol 3,395,469 2.2%
Azelastine 3,334,305 2.2%
Brimonidine 3,271,308 2.2%
Dorzolamide; Timolol 2,482,440 1.6%
Mupirocin 2,373,039 1.6%
Cyclosporine 2,267,431 1.5%
Dorzolamide 2,237,619 1.5%
Erythromycin 2,091,153 1.4%
Nystatin 2,068,647 1.4%
Tretinoin 2,045,305 1.3%
Mometasone 1,954,899 1.3%
Betamethasone 1,934,651 1.3%
Ofloxacin 1,844,983 1.2%
Ketorolac 1,750,298 1.2%
Brimonidine; Timolol 1,661,947 1.1%
Sodium Fluoride 1,559,306 1%
Olopatadine 1,459,568 1%
Chlorhexidine 1,344,171 0.9%
Sodium Salts 1,336,356 0.9%
Fluocinonide 1,282,149 0.8%
Dexamethasone; Moxifloxacin 1,237,556 0.8%
Ketotifen 1,207,446 0.8%
Travoprost 1,036,996 0.7%
Betamethasone; Clotrimazole 1,007,453 0.7%
Fluorouracil 962,262 0.6%
Ipratropium 958,020 0.6%
Neomycin; Polymyxin B; Hydrocortisone 949,592 0.6%
Clotrimazole 839,317 0.6%
Ciclopirox 791,371 0.5%
Bromfenac 777,837 0.5%
Moxifloxacin 763,498 0.5%
Lidocaine 745,363 0.5%
Estrogens, Conjugated (Usp) 743,406 0.5%
Dexamethasone; Neomycin; Polymyxin B 706,702 0.5%
Benzoyl Peroxide; Clindamycin 700,592 0.5%
Loteprednol 688,065 0.5%
Polymyxin B; Trimethoprim 600,900 0.4%
Tacrolimus 554,258 0.4%
Dexamethasone; Tobramycin 527,467 0.3%
Calcipotriene 518,466 0.3%
Hydroquinone 484,505 0.3%
Imiquimod 463,546 0.3%
Lidocaine; Prilocaine 440,877 0.3%
Benzoyl Peroxide 434,768 0.3%
Ciprofloxacin; Dexamethasone 420,670 0.3%
Tobramycin 417,896 0.3%
Silver Sulfadiazine 394,389 0.3%
Lactate 377,493 0.2%
Azelastine; Fluticasone 369,392 0.2%
Adapalene; Benzoyl Peroxide 309,797 0.2%
Desonide 295,846 0.2%
Dapsone 276,517 0.2%
Sulfacetamide; Sulfur 254,801 0.2%
Cromolyn 254,794 0.2%
Adapalene 238,869 0.2%
Azelate 221,814 0.1%
Bacitracin; Neomycin; Polymyxin B 179,559 0.1%
Menthol; Methyl Salicylate 159,995 0.1%
Oxymetazoline 133,894 0.1%
Bacitracin 118,565 0.1%
Ivermectin 116,375 0.1%
Permethrin 103,746 0.1%
Flunisolide 103,220 0.1%
Sulfacetamide 101,959 0.1%
Fluocinolone; Hydroquinone; Tretinoin 100,587 0.1%
Urea 100,480 0.1%
Collagenase 93,358 0.1%
Pyrithione 70,691 0%
Epinastine 61,533 0%
Podofilox 47,955 0%
Salicylic Acid 39,951 0%
Gentamicin 37,567 0%
Hydrogen Peroxide 35,848 0%
Spinosad 29,055 0%
Witch Hazel 21,624 0%
Isopropyl Alcohol 20,351 0%
Povidone Iodine 17,230 0%
Tazarotene 14,361 0%
Silver Acetate 11,307 0%
Cadexomer Iodine 10,997 0%
Bepotastine 8,199 0%
Petrolatum 6,327 0%
Avobenzone; Octocrylene 4,545 0%
Menthol; Camphor 1,488 0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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