Topical Agents

Multum Therapeutic Class Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Fluticasone	22,557,459	15.8%
Estradiol	12,622,776	8.8%
Diclofenac	12,480,263	8.7%
Latanoprost	9,971,002	7%
Triamcinolone	6,216,925	4.3%
Azelastine	5,195,092	3.6%
Metronidazole	4,493,311	3.1%
Prednisolone	4,327,570	3%
Clindamycin	3,855,101	2.7%
Timolol	3,536,136	2.5%
Clobetasol	3,528,926	2.5%
Mupirocin	3,302,564	2.3%
Ketoconazole	2,955,997	2.1%
Cyclosporine	2,478,714	1.7%
Bimatoprost	2,197,512	1.5%
Brimonidine	2,126,111	1.5%
Dorzolamide	2,039,521	1.4%
Hydrocortisone	2,010,949	1.4%
Ofloxacin	1,963,627	1.4%
Sodium Salts	1,776,481	1.2%
Ipratropium	1,718,730	1.2%
Sodium Fluoride	1,706,756	1.2%
Ketorolac	1,681,242	1.2%
Dorzolamide; Timolol	1,606,747	1.1%
Chlorhexidine	1,549,907	1.1%
Nystatin	1,511,024	1.1%
Tretinoin	1,495,701	1%
Betamethasone; Clotrimazole	1,401,057	1%
Ketotifen	1,390,223	1%
Ciclopirox	1,317,601	0.9%
Olopatadine	1,264,679	0.9%
Polymyxin B; Trimethoprim	1,235,661	0.9%
Lidocaine	1,072,085	0.7%
Betamethasone	1,058,996	0.7%
Fluocinonide	1,018,705	0.7%
Hydroquinone	966,577	0.7%
Fluorouracil	924,015	0.6%
Erythromycin	874,052	0.6%
Moxifloxacin	836,135	0.6%
Dexamethasone; Neomycin; Polymyxin B	831,263	0.6%
Silver Sulfadiazine	730,442	0.5%
Tobramycin	633,044	0.4%
Ciprofloxacin; Dexamethasone	543,930	0.4%
Lactate	527,507	0.4%
Adapalene; Benzoyl Peroxide	478,394	0.3%
Neomycin; Polymyxin B; Hydrocortisone	418,235	0.3%
Azelate	395,503	0.3%
Azelastine; Fluticasone	394,381	0.3%
Sulfacetamide; Sulfur	377,314	0.3%
Imiquimod	374,374	0.3%
Oxymetazoline	331,069	0.2%
Benzoyl Peroxide; Clindamycin	299,800	0.2%
Benzoyl Peroxide	278,988	0.2%
Mometasone	264,224	0.2%
Ivermectin	248,599	0.2%
Clascoterone	199,512	0.1%
Cromolyn	199,216	0.1%
Bacitracin	177,089	0.1%
Dapsone	125,394	0.1%
Bepotastine	120,177	0.1%
Adapalene	107,442	0.1%
Menthol; Methyl Salicylate	105,139	0.1%
Aluminum Sulfate; Calcium Acetate	70,990	0%
Trifarotene	53,658	0%
Gentamicin	51,594	0%
Sulfacetamide	49,755	0%
Benzoyl Peroxide; Erythromycin	45,439	0%
Permethrin	43,481	0%
Fluocinolone; Hydroquinone; Tretinoin	43,056	0%
Urea	39,062	0%
Petrolatum	37,111	0%
Pyrithione	36,014	0%
Menthol; Camphor	32,388	0%
Stannous Fluoride	29,105	0%
Collagenase	23,988	0%
Menthol	22,005	0%
Salicylic Acid	18,303	0%
Ketoprofen	15,834	0%
Benzoyl Peroxide; Tretinoin	15,002	0%
Lanolin; Petrolatum	10,607	0%
Bacitracin; Neomycin; Polymyxin B	9,024	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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