Topical Agents

Multum Therapeutic Class Comparison, United States, 2019

Total Prescriptions in (2019)

Drug Name Total Prescriptions (2019) Percent Share
Fluticasone 27,893,103 16.3%
Estradiol 12,393,425 7.2%
Diclofenac 10,115,975 5.9%
Latanoprost 9,800,570 5.7%
Triamcinolone 6,320,752 3.7%
Ciprofloxacin 5,878,441 3.4%
Clindamycin 5,588,598 3.3%
Metronidazole 4,664,908 2.7%
Prednisolone 4,638,327 2.7%
Hydrocortisone 4,382,981 2.6%
Timolol 3,833,125 2.2%
Azelastine 3,669,768 2.1%
Ketoconazole 3,573,982 2.1%
Clobetasol 3,226,424 1.9%
Mupirocin 3,064,119 1.8%
Cyclosporine 2,889,776 1.7%
Dorzolamide; Timolol 2,590,910 1.5%
Brimonidine 2,290,789 1.3%
Lidocaine 2,273,902 1.3%
Nystatin 2,185,148 1.3%
Sodium 2,117,734 1.2%
Ofloxacin 2,051,823 1.2%
Erythromycin 2,041,420 1.2%
Brimonidine; Timolol 1,990,438 1.2%
Tretinoin 1,937,920 1.1%
Ipratropium 1,898,298 1.1%
Bimatoprost 1,697,723 1%
Mometasone 1,638,402 1%
Dorzolamide 1,615,873 0.9%
Ketorolac 1,602,924 0.9%
Olopatadine 1,561,993 0.9%
Tobramycin; Dexamethasone 1,486,152 0.9%
Polymyxin B; Trimethoprim 1,450,395 0.8%
Betamethasone 1,311,107 0.8%
Chlorhexidine 1,295,646 0.8%
Fluocinonide 1,290,749 0.8%
Ciclopirox 1,285,508 0.8%
Travoprost 1,264,925 0.7%
Sodium Fluoride 1,110,641 0.6%
Clotrimazole 1,046,204 0.6%
Neomycin; Polymyxin B; Hydrocortisone 978,292 0.6%
Dexamethasone; Neomycin; Polymyxin B 957,525 0.6%
Azelastine; Fluticasone 794,966 0.5%
Tobramycin 751,695 0.4%
Difluprednate 717,462 0.4%
Loteprednol 699,881 0.4%
Silver Sulfadiazine 681,657 0.4%
Moxifloxacin 666,289 0.4%
Fluorouracil 642,442 0.4%
Betamethasone; Clotrimazole 631,823 0.4%
Benzoyl Peroxide 626,562 0.4%
Estrogens, Conjugated (Usp) 608,837 0.4%
Adapalene; Benzoyl Peroxide 582,026 0.3%
Ciprofloxacin; Dexamethasone 515,590 0.3%
Lactate 505,469 0.3%
Benzoyl Peroxide; Clindamycin 466,107 0.3%
Bromfenac 445,185 0.3%
Fluorometholone 434,532 0.3%
Oxymetazoline 406,258 0.2%
Ketotifen 403,117 0.2%
Glycerin 363,289 0.2%
Imiquimod 361,964 0.2%
Calcipotriene 349,102 0.2%
Permethrin 331,521 0.2%
Hydroquinone 329,796 0.2%
Fluocinolone 313,716 0.2%
Gentamicin 306,262 0.2%
Cromolyn 287,958 0.2%
Dapsone 283,103 0.2%
Bacitracin; Neomycin; Polymyxin B 273,131 0.2%
Desonide 253,688 0.1%
Nystatin; Triamcinolone 219,822 0.1%
Epinastine 182,493 0.1%
Urea 174,364 0.1%
Menthol 174,316 0.1%
Bacitracin 147,507 0.1%
Ivermectin 146,213 0.1%
Petrolatum 144,553 0.1%
Adapalene 126,474 0.1%
Salicylic Acid 121,128 0.1%
Sulfacetamide; Sulfur 117,250 0.1%
Naphazoline; Pheniramine 104,840 0.1%
Menthol; Methyl Salicylate 98,735 0.1%
Azelate 63,352 0%
Bacitracin; Polymyxin B 62,976 0%
Camphor; Menthol; Methyl Salicylate 57,884 0%
Benzethonium 41,257 0%
Collagenase 39,409 0%
Benzoyl Peroxide; Erythromycin 27,333 0%
Sulfacetamide 26,879 0%
Aluminum Sulfate; Calcium Acetate 25,942 0%
Tazarotene 21,448 0%
Stannous Fluoride 19,145 0%
Trolamine Salicylate 16,843 0%
Bepotastine 16,605 0%
Hypochlorite 13,649 0%
Sinecatechins 7,740 0%
Podofilox 7,070 0%
Tetrahydrozoline 6,420 0%
Menthol; Camphor 4,792 0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2019. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2021.10. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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