Topical Agents

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name	Total Prescriptions (2020)	Percent Share
Fluticasone	24,777,490	16.3%
Estradiol	11,307,656	7.4%
Diclofenac	9,926,750	6.5%
Latanoprost	9,722,631	6.4%
Triamcinolone	6,422,562	4.2%
Clindamycin	5,131,000	3.4%
Timolol	4,295,413	2.8%
Hydrocortisone	3,998,412	2.6%
Prednisolone	3,894,469	2.6%
Bimatoprost	3,483,064	2.3%
Ketoconazole	3,417,349	2.3%
Clobetasol	3,395,469	2.2%
Azelastine	3,334,305	2.2%
Brimonidine	3,271,308	2.2%
Dorzolamide; Timolol	2,482,440	1.6%
Mupirocin	2,373,039	1.6%
Cyclosporine	2,267,431	1.5%
Dorzolamide	2,237,619	1.5%
Erythromycin	2,091,153	1.4%
Nystatin	2,068,647	1.4%
Tretinoin	2,045,305	1.3%
Mometasone	1,954,899	1.3%
Betamethasone	1,934,651	1.3%
Ofloxacin	1,844,983	1.2%
Ketorolac	1,750,298	1.2%
Brimonidine; Timolol	1,661,947	1.1%
Sodium Fluoride	1,559,306	1%
Olopatadine	1,459,568	1%
Chlorhexidine	1,344,171	0.9%
Sodium Salts	1,336,356	0.9%
Fluocinonide	1,282,149	0.8%
Dexamethasone; Moxifloxacin	1,237,556	0.8%
Ketotifen	1,207,446	0.8%
Travoprost	1,036,996	0.7%
Betamethasone; Clotrimazole	1,007,453	0.7%
Fluorouracil	962,262	0.6%
Ipratropium	958,020	0.6%
Neomycin; Polymyxin B; Hydrocortisone	949,592	0.6%
Clotrimazole	839,317	0.6%
Ciclopirox	791,371	0.5%
Bromfenac	777,837	0.5%
Moxifloxacin	763,498	0.5%
Lidocaine	745,363	0.5%
Estrogens, Conjugated (Usp)	743,406	0.5%
Dexamethasone; Neomycin; Polymyxin B	706,702	0.5%
Benzoyl Peroxide; Clindamycin	700,592	0.5%
Loteprednol	688,065	0.5%
Polymyxin B; Trimethoprim	600,900	0.4%
Tacrolimus	554,258	0.4%
Dexamethasone; Tobramycin	527,467	0.3%
Calcipotriene	518,466	0.3%
Hydroquinone	484,505	0.3%
Imiquimod	463,546	0.3%
Lidocaine; Prilocaine	440,877	0.3%
Benzoyl Peroxide	434,768	0.3%
Ciprofloxacin; Dexamethasone	420,670	0.3%
Tobramycin	417,896	0.3%
Silver Sulfadiazine	394,389	0.3%
Lactate	377,493	0.2%
Azelastine; Fluticasone	369,392	0.2%
Adapalene; Benzoyl Peroxide	309,797	0.2%
Desonide	295,846	0.2%
Dapsone	276,517	0.2%
Sulfacetamide; Sulfur	254,801	0.2%
Cromolyn	254,794	0.2%
Adapalene	238,869	0.2%
Azelate	221,814	0.1%
Bacitracin; Neomycin; Polymyxin B	179,559	0.1%
Menthol; Methyl Salicylate	159,995	0.1%
Oxymetazoline	133,894	0.1%
Bacitracin	118,565	0.1%
Ivermectin	116,375	0.1%
Permethrin	103,746	0.1%
Flunisolide	103,220	0.1%
Sulfacetamide	101,959	0.1%
Fluocinolone; Hydroquinone; Tretinoin	100,587	0.1%
Urea	100,480	0.1%
Collagenase	93,358	0.1%
Pyrithione	70,691	0%
Epinastine	61,533	0%
Podofilox	47,955	0%
Salicylic Acid	39,951	0%
Gentamicin	37,567	0%
Hydrogen Peroxide	35,848	0%
Spinosad	29,055	0%
Witch Hazel	21,624	0%
Isopropyl Alcohol	20,351	0%
Povidone Iodine	17,230	0%
Tazarotene	14,361	0%
Silver Acetate	11,307	0%
Cadexomer Iodine	10,997	0%
Bepotastine	8,199	0%
Petrolatum	6,327	0%
Avobenzone; Octocrylene	4,545	0%
Menthol; Camphor	1,488	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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