Psychotherapeutic Agents

Multum Therapeutic Class Comparison, United States, 2021

Total Prescriptions in (2021)

Drug Name Total Prescriptions (2021) Percent Share
Sertraline 39,206,398 15.4%
Escitalopram 30,505,719 12%
Bupropion 29,099,445 11.4%
Trazodone 26,310,083 10.3%
Fluoxetine 22,686,839 8.9%
Duloxetine 20,012,842 7.9%
Citalopram 18,444,406 7.3%
Venlafaxine 15,122,967 5.9%
Quetiapine 10,957,923 4.3%
Paroxetine 7,482,340 2.9%
Aripiprazole 6,805,675 2.7%
Amitriptyline 5,923,315 2.3%
Mirtazapine 4,752,293 1.9%
Risperidone 4,225,630 1.7%
Nortriptyline 4,183,946 1.6%
Olanzapine 3,347,385 1.3%
Desvenlafaxine 2,781,884 1.1%
Lurasidone 2,433,438 1%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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