Psychotherapeutic Agents

Multum Therapeutic Class Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name Total Prescriptions (2022) Percent Share
Sertraline 39,891,990 16.4%
Escitalopram 30,750,612 12.6%
Trazodone 27,363,318 11.3%
Bupropion 25,197,923 10.4%
Fluoxetine 24,014,263 9.9%
Duloxetine 18,066,468 7.4%
Citalopram 15,047,663 6.2%
Venlafaxine 13,881,023 5.7%
Quetiapine 8,443,015 3.5%
Amitriptyline 7,887,977 3.2%
Paroxetine 7,127,749 2.9%
Mirtazapine 6,069,480 2.5%
Aripiprazole 6,053,911 2.5%
Olanzapine 3,028,056 1.2%
Risperidone 2,609,294 1.1%
Nortriptyline 2,256,836 0.9%
Desvenlafaxine 1,947,177 0.8%
Lithium 1,861,585 0.8%
Doxepin 1,729,966 0.7%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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