Psychotherapeutic Agents

Multum Therapeutic Class Comparison, United States, 2024

Total Prescriptions in (2024)

Drug Name	Total Prescriptions (2024)	Percent Share
Sertraline	44,634,056	16.1%
Escitalopram	41,773,079	15.1%
Bupropion	34,895,515	12.6%
Fluoxetine	29,517,276	10.6%
Trazodone	26,159,532	9.4%
Duloxetine	17,860,264	6.4%
Venlafaxine	16,273,306	5.9%
Citalopram	12,500,215	4.5%
Quetiapine	8,669,046	3.1%
Aripiprazole	8,246,932	3%
Amitriptyline	7,533,046	2.7%
Paroxetine	7,173,802	2.6%
Mirtazapine	5,605,882	2%
Desvenlafaxine	3,875,578	1.4%
Olanzapine	3,642,411	1.3%
Lithium	3,301,040	1.2%
Nortriptyline	3,297,511	1.2%
Risperidone	2,272,519	0.8%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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