Gastrointestinal Agents

Multum Therapeutic Class Comparison, United States, 2023

Total Prescriptions in (2023)

Drug Name	Total Prescriptions (2023)	Percent Share
Omeprazole	45,290,896	34.2%
Pantoprazole	37,101,751	28%
Famotidine	16,883,437	12.8%
Esomeprazole	3,828,169	2.9%
Docusate	3,798,216	2.9%
Linaclotide	2,817,174	2.1%
Dicyclomine	2,561,310	1.9%
Polyethylene Glycol 3350	2,491,296	1.9%
Calcium	2,427,416	1.8%
Mesalamine	2,365,207	1.8%
Sodium Salts	1,698,018	1.3%
Sucralfate	1,487,376	1.1%
Senna; Docusate	1,440,174	1.1%
Metoclopramide	1,116,508	0.8%
Pancrelipase Amylase; Pancrelipase Lipase; Pancrelipase Protease	1,076,565	0.8%
Lactulose	966,210	0.7%
Polyethylene Glycol 3350 With Electrolytes	842,998	0.6%
Loperamide	822,307	0.6%
Atropine; Diphenoxylate	614,353	0.5%
Bisacodyl	481,189	0.4%
Riboflavin	451,740	0.3%
Lactobacillus Acidophilus	445,217	0.3%
Psyllium	407,080	0.3%
Sennosides	385,650	0.3%
Magnesium	275,417	0.2%
Saccharomyces Boulardii	126,357	0.1%
Bismuth Subsalicylate	50,953	0%
Aluminum Hydroxide	13,533	0%
Anhydrous Citric Acid; Magnesium Oxide; Sodium Picosulfate	9,111	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2023. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2025.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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