Cardiovascular Agents

Multum Therapeutic Class Comparison, United States, 2021

Total Prescriptions in (2021)

Drug Name Total Prescriptions (2021) Percent Share
Lisinopril 88,272,557 15.8%
Amlodipine 73,569,607 13.2%
Metoprolol 65,529,551 11.7%
Losartan 55,245,075 9.9%
Hydrochlorothiazide 39,038,823 7%
Furosemide 26,376,405 4.7%
Tamsulosin 23,540,060 4.2%
Carvedilol 21,782,178 3.9%
Atenolol 14,107,488 2.5%
Hydrochlorothiazide; Lisinopril 12,908,560 2.3%
Spironolactone 12,688,242 2.3%
Clonidine 8,613,723 1.5%
Diltiazem 8,522,822 1.5%
Hydrochlorothiazide; Losartan 8,266,619 1.5%
Propranolol 7,993,156 1.4%
Hydralazine 6,234,196 1.1%
Isosorbide 5,601,960 1%
Hydrochlorothiazide; Triamterene 5,428,907 1%
Valsartan 5,151,116 0.9%
Olmesartan 4,581,363 0.8%
Chlorthalidone 4,577,163 0.8%
Nifedipine 4,567,479 0.8%
Benazepril 3,932,102 0.7%
Amlodipine; Benazepril 3,883,604 0.7%
Sildenafil 3,613,744 0.6%
Tadalafil 3,167,762 0.6%
Irbesartan 3,148,186 0.6%
Nitroglycerin 2,842,773 0.5%
Torsemide 2,753,010 0.5%
Prazosin 2,692,450 0.5%
Sacubitril; Valsartan 2,591,807 0.5%
Doxazosin 2,340,071 0.4%
Verapamil 2,339,847 0.4%
Ramipril 2,305,402 0.4%
Flecainide 2,199,320 0.4%
Labetalol 2,019,527 0.4%
Telmisartan 1,954,207 0.3%
Ranolazine 1,910,445 0.3%
Epinephrine 1,896,954 0.3%
Hydrochlorothiazide; Valsartan 1,871,393 0.3%
Guanfacine 1,771,668 0.3%
Terazosin 1,729,967 0.3%
Amiodarone 1,713,448 0.3%
Digoxin 1,594,793 0.3%
Nebivolol 1,554,153 0.3%
Enalapril 832,753 0.1%
Phenylephrine 18,861 0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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