Anxiolytics, Sedatives, and Hypnotics

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name	Total Prescriptions (2020)	Percent Share
Alprazolam	16,780,806	18.1%
Clonazepam	14,758,212	15.9%
Zolpidem	14,272,253	15.4%
Buspirone	11,820,023	12.7%
Lorazepam	10,559,374	11.4%
Hydroxyzine	10,058,837	10.8%
Diazepam	4,972,397	5.4%
Diphenhydramine	2,614,774	2.8%
Temazepam	2,143,561	2.3%
Eszopiclone	1,937,205	2.1%
Doxepin	1,721,844	1.9%
Melatonin	1,090,897	1.2%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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