Anxiolytics, Sedatives, and Hypnotics

Multum Therapeutic Class Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Alprazolam	14,988,527	19%
Hydroxyzine	13,652,752	17.3%
Buspirone	12,332,590	15.6%
Clonazepam	11,711,066	14.9%
Zolpidem	9,972,232	12.7%
Lorazepam	8,502,480	10.8%
Diazepam	3,093,210	3.9%
Melatonin	1,733,014	2.2%
Doxepin	1,729,966	2.2%
Diphenhydramine	1,091,279	1.4%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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