Antihistamines

Multum Therapeutic Class Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Cetirizine	13,899,342	30%
Hydroxyzine	13,652,752	29.4%
Loratadine	9,230,348	19.9%
Levocetirizine	3,646,727	7.9%
Promethazine	2,149,358	4.6%
Fexofenadine	1,095,266	2.4%
Diphenhydramine	1,091,279	2.4%
Chlorpheniramine	487,007	1%
Cyproheptadine	473,480	1%
Fexofenadine; Pseudoephedrine	342,583	0.7%
Desloratadine	241,068	0.5%
Dexbrompheniramine	61,238	0.1%
Triprolidine	31,768	0.1%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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