Antihistamines

Multum Therapeutic Class Comparison, United States, 2024

Total Prescriptions in (2024)

Drug Name	Total Prescriptions (2024)	Percent Share
Hydroxyzine	14,857,241	31.3%
Cetirizine	14,363,215	30.3%
Loratadine	6,962,604	14.7%
Levocetirizine	4,423,399	9.3%
Promethazine	2,216,343	4.7%
Fexofenadine	1,556,204	3.3%
Cyproheptadine	1,222,741	2.6%
Diphenhydramine	913,286	1.9%
Desloratadine	409,405	0.9%
Chlorpheniramine	335,410	0.7%
Triprolidine	145,452	0.3%
Carbinoxamine	36,467	0.1%
Dexbrompheniramine	33,859	0.1%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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