Antidepressants

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name Total Prescriptions (2020) Percent Share
Sertraline 38,219,814 16%
Escitalopram 30,605,647 12.8%
Bupropion 28,889,369 12.1%
Trazodone 26,210,732 11%
Fluoxetine 23,403,050 9.8%
Duloxetine 22,546,921 9.4%
Citalopram 18,549,177 7.8%
Venlafaxine 15,022,424 6.3%
Amitriptyline 9,083,402 3.8%
Paroxetine 9,029,668 3.8%
Mirtazapine 6,601,132 2.8%
Nortriptyline 3,815,025 1.6%
Desvenlafaxine 3,267,575 1.4%
Vortioxetine 1,826,352 0.8%
Doxepin 1,721,844 0.7%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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