Antidepressants

Multum Therapeutic Class Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name	Total Prescriptions (2020)	Percent Share
Sertraline	38,219,814	16%
Escitalopram	30,605,647	12.8%
Bupropion	28,889,369	12.1%
Trazodone	26,210,732	11%
Fluoxetine	23,403,050	9.8%
Duloxetine	22,546,921	9.4%
Citalopram	18,549,177	7.8%
Venlafaxine	15,022,424	6.3%
Amitriptyline	9,083,402	3.8%
Paroxetine	9,029,668	3.8%
Mirtazapine	6,601,132	2.8%
Nortriptyline	3,815,025	1.6%
Desvenlafaxine	3,267,575	1.4%
Vortioxetine	1,826,352	0.8%
Doxepin	1,721,844	0.7%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Gorillas can't learn drug therapy ... but you can. The Top 250 Drugs by ClinCalc Academy

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Updated Sep 12, 2021

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