Analgesics

Multum Therapeutic Class Comparison, United States, 2023

Total Prescriptions in (2023)

Drug Name	Total Prescriptions (2023)	Percent Share
Acetaminophen; Hydrocodone	21,506,769	13.4%
Meloxicam	20,703,690	12.9%
Ibuprofen	17,525,800	10.9%
Tramadol	16,010,294	10%
Aspirin	14,095,182	8.8%
Oxycodone	13,502,067	8.4%
Diclofenac	9,438,697	5.9%
Acetaminophen; Oxycodone	7,283,472	4.5%
Naproxen	6,808,487	4.2%
Sumatriptan	6,484,250	4%
Celecoxib	6,190,144	3.8%
Acetaminophen	5,984,655	3.7%
Morphine	3,500,074	2.2%
Rimegepant	2,263,880	1.4%
Rizatriptan	2,219,595	1.4%
Acetaminophen; Codeine	2,189,480	1.4%
Ketorolac	1,627,126	1%
Acetaminophen; Butalbital; Caffeine	1,039,901	0.6%
Nabumetone	869,464	0.5%
Indomethacin	593,609	0.4%
Etodolac	450,221	0.3%
Codeine	202,788	0.1%
Sulindac	168,142	0.1%
Hydrocodone	79,852	0%
Oxaprozin	72,993	0%
Diclofenac; Misoprostol	47,412	0%
Aspirin; Citric Acid; Sodium Bicarbonate	10,494	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2023. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2025.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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