Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Established Pharmacologic Class (EPC) Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Dextromethorphan; Promethazine	1,088,232	36.9%
Brompheniramine; Dextromethorphan; Pseudoephedrine	1,039,412	35.3%
Dextromethorphan; Guaifenesin	487,450	16.5%
Dextromethorphan	158,061	5.4%
Dextromethorphan; Guaifenesin; Phenylephrine	54,843	1.9%
Dexchlorpheniramine; Dextromethorphan; Phenylephrine	36,371	1.2%
Chlorpheniramine; Dextromethorphan; Phenylephrine	30,391	1%
Brompheniramine; Dextromethorphan; Phenylephrine	19,849	0.7%
Dexbrompheniramine; Dextromethorphan; Phenylephrine	17,778	0.6%
Dextromethorphan; Pheniramine; Phenylephrine	16,261	0.6%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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