Serotonin Reuptake Inhibitor

Established Pharmacologic Class (EPC) Comparison, United States, 2019

Total Prescriptions in (2019)

Drug Name Total Prescriptions (2019) Percent Share
Sertraline 37,157,934 25.3%
Escitalopram 27,510,959 18.7%
Fluoxetine 27,110,302 18.4%
Trazodone 23,934,214 16.3%
Citalopram 21,546,700 14.7%
Paroxetine 9,783,756 6.7%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2019. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2021.10. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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