Opioid Agonist

Established Pharmacologic Class (EPC) Comparison, United States, 2018

Total Prescriptions in (2018)

Drug Name Total Prescriptions (2018) Percent Share
Acetaminophen; Hydrocodone Bitartrate 42,073,176 44.3%
Tramadol Hydrochloride 24,952,328 26.3%
Oxycodone 16,967,480 17.9%
Morphine 5,225,089 5.5%
Hydromorphone Hydrochloride 2,378,610 2.5%
Fentanyl 1,296,491 1.4%
Codeine Sulfate 1,043,643 1.1%
Loperamide Hydrochloride 582,891 0.6%
Hydrocodone Bitartrate 404,996 0.4%
Hydrocodone; Chlorpheniramine 84,068 0.1%

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.0. Read more about the ClinCalc DrugStats database.

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Updated Jul 19, 2018
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