Nonsteroidal Anti-inflammatory Drug

Established Pharmacologic Class (EPC) Comparison, United States, 2018

Total Prescriptions in (2018)

Drug Name	Total Prescriptions (2018)	Percent Share
Ibuprofen	24,453,501	27.9%
Meloxicam	22,610,690	25.8%
Naproxen	11,942,766	13.6%
Diclofenac	11,372,070	13%
Celecoxib	5,445,346	6.2%
Ketorolac Tromethamine	3,085,293	3.5%
Indomethacin	2,160,197	2.5%
Bromfenac Sodium; Prednisolone Acetate; Gatifloxacin	1,638,403	1.9%
Nabumetone	1,554,892	1.8%
Etodolac	951,331	1.1%
Bromfenac Sodium	743,397	0.8%
Nepafenac	519,404	0.6%
Flurbiprofen	381,836	0.4%
Sulindac	219,400	0.3%
Diclofenac Sodium; Misoprostol	157,707	0.2%
Diflunisal	149,023	0.2%
Piroxicam	133,990	0.2%
Oxaprozin	35,890	0%

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Which of these drugs is contraindicated in pregnancy? The Top 250 Drugs by ClinCalc Academy

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Updated Jan 18, 2021

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