Nonsteroidal Anti-inflammatory Drug

Established Pharmacologic Class (EPC) Comparison, United States, 2022

Total Prescriptions in (2022)

Drug Name	Total Prescriptions (2022)	Percent Share
Meloxicam	18,859,721	22.2%
Ibuprofen	17,493,911	20.6%
Aspirin	16,981,811	20%
Diclofenac	12,480,263	14.7%
Naproxen	7,381,940	8.7%
Celecoxib	7,023,512	8.3%
Ketorolac	1,681,242	2%
Nabumetone	1,463,756	1.7%
Indomethacin	1,097,589	1.3%
Sulindac	260,923	0.3%
Etodolac	257,226	0.3%
Diclofenac; Misoprostol	25,434	0%
Ketoprofen	15,834	0%
Oxaprozin	11,605	0%
Piroxicam	4,972	0%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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