Central alpha-2 Adrenergic Agonist

Established Pharmacologic Class (EPC) Comparison, United States, 2019

Total Prescriptions in (2019)

Drug Name Total Prescriptions (2019) Percent Share
Clonidine 11,418,367 46.1%
Tizanidine 8,729,695 35.3%
Guanfacine 4,608,026 18.6%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time


Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2019. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2021.10. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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