Central Nervous System Stimulant

Established Pharmacologic Class (EPC) Comparison, United States, 2020

Total Prescriptions in (2020)

Drug Name	Total Prescriptions (2020)	Percent Share
Dextroamphetamine; Dextroamphetamine Saccharate; Amphetamine; Amphetamine Aspartate	26,080,152	45.3%
Methylphenidate	15,449,350	26.8%
Lisdexamfetamine	8,647,784	15%
Dexmethylphenidate	4,802,552	8.3%
Acetaminophen; Butalbital; Caffeine	2,396,593	4.2%
Amphetamine	163,177	0.3%

Total Prescriptions by Drug Over Time

Drug Class Prescribing Trends Over Time

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021

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