Drug Usage Statistics, United States, 2013 - 2020

Desvenlafaxine Summary for 2020

Top drug rank #176 ( 2)
Estimated number of prescriptions in the United States (2020) 3,267,575
Estimated number of patients in the United States (2020) 624,316
Average total drug cost (USD)  
Per prescription $66.92
Per day of therapy $2.07/day
Average out-of-pocket cost (USD)  
Per prescription $14.78
Per day of therapy $0.45/day

Total Prescriptions and Patients Per Year (2013 - 2020)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 185  15
2014 203  18
2015 240  37
2016 278  38
Year Rank Change
2017 240  38
2018 213  27
2019 178  35
2020 176  2

Drug Cost Over Time (2013 - 2020)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2020)

Dosage Form Strength % of Dispensed Products
Tablet/capsule 50 mg 62.8%
Tablet/capsule 100 mg 26.8%
Tablet/capsule 25 mg 10.4%

Distribution of Days Supplied (2020)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2020)
Duloxetine 22,546,921
Venlafaxine 15,022,424
Desvenlafaxine (this drug) 3,267,575

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Khedezla
  • Desvenlafaxine
  • Pristiq
Generic Drug Synonyms and Salts
  • Desvenlafaxine Fumarate
  • Desvenlafaxine Fumarate Monohydrate
  • Desvenlafaxine Succinate
  • Desvenlafaxine

FDA Approval Information

Established Pharmacologic Class (EPC): Serotonin and Norepinephrine Reuptake Inhibitor
Initial FDA approval date: 2/29/2008
First FDA applicant: Rx
First dosage form: Tablet, Extended Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2020. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2022.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Sep 12, 2021
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