Drug Usage Statistics, United States, 2006 - 2016

Number of Prescriptions Over Time (2006 - 2016)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2006 347  21
2007 324  23
2008 337  13
2009 335  2
2010 335 0
2011 287  48
Year Rank Change
2012 304  17
2013 323  19
2014 335  12
2015 332  3
2016 297  35

Patient Out-Of-Pocket Cost Over Time (2006 - 2016)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2016)
Tretinoin (this drug) 1,249,141
Isotretinoin 1,118,664
Adapalene 427,499
Adapalene; Benzoyl Peroxide 352,797

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Altreno
  • Atralin
  • Avita
  • Renova
  • Retin-a
  • Retin-a Micro
  • Retin-a-micro
  • Vesanoid
Generic Drug Synonyms and Salts
  • Tretinoin

FDA Approval Information

Established Pharmacologic Class (EPC): Retinoid
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Rx
First dosage form: Cream (topical)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2006-2016. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 19.1. Read more about the ClinCalc DrugStats database.


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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Jul 19, 2018
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