Sulfamethoxazole; Trimethoprim

Drug Usage Statistics, United States, 2008 - 2018

Sulfamethoxazole; Trimethoprim Summary for 2018

Estimated number of prescriptions in the United States 8,448,278
Top drug rank #91 ( 30)
Average total drug cost $10.01 (USD)
Average out-of-pocket cost $3.46 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 114  11
2009 114 0
2010 120  6
2011 128  8
2012 106  22
2013 102  4
Year Rank Change
2014 112  10
2015 73  39
2016 106  33
2017 121  15
2018 91  30

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Sulfamethoxazole; Trimethoprim (this drug) 8,448,279
Polymyxin B Sulfate; Trimethoprim Sulfate 1,703,424
Trimethoprim 96,945

Multum Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Bactrim
  • Bactrim DS
  • Bactrim Pediatric
  • Cotrim
  • Cotrim D.S.
  • Septra
  • Septra DS
  • Septra Grape
  • Sulfamethoprim
  • Sulfamethoprim-DS
  • Sulfamethoxazole And Trimethoprim
  • Sulfamethoxazole And Trimethoprim Double Strength
  • Sulfamethoxazole And Trimethoprim Single Strength
  • Sulfatrim
  • Sulfatrim Pediatric
  • Sulfatrim-DS
  • Sulfatrim-SS
  • Sulmeprim
  • Sulmeprim Pediatric
  • Trimeth/Sulfa
  • Uroplus DS
  • Uroplus SS
Generic Drug Synonyms and Salts
  • Trimethoprim; Sulfamethoxazole
  • Sulfamethoxazole; Trimethoprim

FDA Approval Information

Established Pharmacologic Class (EPC): Sulfonamide Antimicrobial, Dihydrofolate Reductase Inhibitor Antibacterial
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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