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Sodium Fluoride

Drug Usage Statistics, United States, 2014 - 2023

ClinCalc.com » Pharmacy » ClinCalc DrugStats » Sodium Fluoride

Sodium Fluoride Summary for 2023

Top drug rank #264 ( 43)
Estimated number of prescriptions in the United States (2023) 1,037,661
Estimated number of patients in the United States (2023) 559,898
 
Average total drug cost (USD)  
Per prescription $15.88
Per day of therapy $0.50/day
Average out-of-pocket cost (USD)  
Per prescription $12.72
Per day of therapy $0.39/day

Total Prescriptions and Patients Per Year (2014 - 2023)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2014 172  110
2015 202  30
2016 224  22
2017 256  32
2018 268  12
Year Rank Change
2019 319  51
2020 265  54
2021 291  26
2022 221  70
2023 264  43

Drug Cost Over Time (2014 - 2023)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.
  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2023)

Dosage Form Strength % of Dispensed Products
Paste 1.1% 55.2%
Tablet/capsule 1 mg 17.9%
Cream 1.1% 11.9%
Other, unspecified, or misc. 15.0%

Distribution of Days Supplied (2023)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2023)
Sodium Fluoride (this drug) 1,037,662

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • A And H Plus Therabreath Breath Freshners
  • Act Anticavity Fluoride Arctic Blast
  • Act Anticavity Fluoride Cinnamon
  • Act Anticavity Fluoride Kids Bubblegum
  • Act Anticavity Fluoride Kids Groovy Grape
  • Act Anticavity Fluoride Kids Wild Watermelon
  • Act Anticavity Fluoride Mint
  • Act Kids Anticavity Fluoride
  • Act Kids Anticavity Fluoride Groovy Grape
  • Act Kids Anticavity Fluoride Pineapple Punch
  • Act Kids Pure Protect Anticavity- Simply Strawberry
  • Act Restoring Anticavity Fluoride Cool Mint
  • Act Restoring Anticavity Fluoride Mint Burst
  • Act Total Care Anticavity Fluoride Fresh Mint
  • Act Total Care Anticavity Fluoride Icy Clean Mint
  • Act Total Care Dry Mouth Anticavity Mouth
  • Act Whitening Anticavity Gentle Mint
  • Adoptaplatoon
  • Advance White
  • Advance White Extreme Whitening
  • Aim
  • Aim Cavity Protection
  • Aim Tartar Control
  • Aim Whitening
  • Alcohol Free Refreshing Mint
  • Alcohol-free Anticavity
  • Amerfresh
  • Amerfresh Fluoride
  • Amerfresh Fluoride Gel
  • Amerfresh Tooth
  • Anticavity
  • Anticavity Fluoride
  • Anticavity Fluoride Rinse
  • Anticavity Rinse
  • AP-24
  • Aquafresh
  • Arc
  • Astonea -Sodium Fluoride
  • Autobrush Bubblegum
  • Autobrush Mint
  • Autobrush Strawberry
  • Autobrush Watermelon
  • Avon Whitening Essentials
  • Barbie Bubble Gum Anticavity Fluoride
  • Beyond Activated Coconut Charcoal And Sea Salt
  • Bio Spectra
  • Biotene
  • Botao Kids Strawberry Flavored With Fluoride
  • Brush Buddies - Hot Wheels Anticavity Fluoride
  • Brush Buddies Advanced Whitening Anti-cavity Fluoride Peppermint
  • Brush Buddies Barbie Anticavity Fluoride - Bubble Gum Flavor
  • Brush Buddies Barbie Anticavity Fluoride Bubblegum
  • Brush Buddies Brbie Anticavity Fluoride Bubblegum
  • Brush Buddies Crayola Anticavity Fluoride - Bubble Gum Flavor
  • Brush Buddies Crayola Anticavity Fluoride - Strawberry Flavor
  • Brush Buddies Crayola Anticavity Fluoride - Watermelon Flavor
  • Brush Buddies Crayola Anticavity Fluoride Bubblegum
  • Brush Buddies Crayola Anticavity Fluoride Strawberry
  • Brush Buddies Crayola Anticavity Fluoride Watermelon
  • Brush Buddies Crayola Swirl Anticavity Fluoride Watermelon Flavor
  • Brush Buddies Hot Wheels Anticavity Fluoride - Strawberry Flavor
  • Brush Buddies Hotwheel Anticavity Fluoride Strawberry
  • Brush Buddies MY Little Pony Anticavity Fluoride
  • Brush Buddies Oral Rinse Sparkle Mint
  • Brush Buddies Squishmallows Anticavity Fluoride Mint Falvor
  • Brush Buddies Squishmallows Anticavity Fluoride Mint Flavor
  • Bubble Gum Flavor For Kids 25g 50g
  • Burts Bees
  • Burts Bees Kids
  • Cardinal Health
  • Cavity Protection Fresh Mint
  • Cavity Protection Fresh Mint Anticavity Mouthwash
  • Charm Tex Fluoride Gel
  • Charm-tex Fluoride Gel
  • Cinnafresh
  • Clinpro Tooth Creme
  • Close UP
  • Closys
  • Closys Silver Sensitive Mouth Rinse
  • Cloveden Sensitive Care Tooth
  • Colgate
  • Colgate 2 IN 1 Kids SP Strawberry
  • Colgate 2in1
  • Colgate Cavity Protection
  • Colgate Cavity Protection Fresh Mint
  • Colgate Deep Clean Fluoride
  • Colgate Enamel Health Mouthwash
  • Colgate Enamel Strength Mouthwash
  • Colgate Junior Bubble Fruit
  • Colgate Junior Kids Batman Mild Bubble Fruit Fluoride
  • Colgate Junior Mixed Kids Bubble Fruit Fluoride
  • Colgate Kids
  • Colgate Kids Llama
  • Colgate Kids Maximum Cavity Protection
  • Colgate Kids Maximum Cavity Protection Batman
  • Colgate Kids Minions Mouthwash
  • Colgate Kids Space Jam
  • Colgate Kids Unicorn Alcohol Free
  • Colgate Kids Watermelon Flavor
  • Colgate Max Fresh
  • Colgate Max Fresh Clean Mint
  • Colgate Max Fresh Cool Mint
  • Colgate Maxclean With Whitening Smartfoam
  • Colgate Maxfresh Charcoal
  • Colgate Maxfresh Citrus Fresh
  • Colgate Maxfresh Clean Mint
  • Colgate Maxfresh Cool Mint
  • Colgate Maxfresh Knockout
  • Colgate Maxfresh Watermelon Blast
  • Colgate Maxfresh With Mini Breath Clean Mint
  • Colgate Maxfresh With Mini Breath Cool Mint
  • Colgate Maximum Cavity Protection
  • Colgate Minions Mild Bubble Fruit Fluoride
  • Colgate Optic White Charcoal
  • Colgate Optic White Stain Fighter
  • Colgate Optic White Stain Fighter Clean Mint
  • Colgate Optic White Stain Fighter Fresh Mint
  • Colgate Optic White Stain Fighter Sens Relief
  • Colgate Optic White Stain Fighter With Baking Soda
  • Colgate Phos-flur Ortho Defense Alcohol Free Anticavity Gushing Grape Fluoride
  • Colgate Phos-flur Ortho Defense Alcohol Free Anticavity Mint Fluoride
  • Colgate Sparkling White Cinnamint
  • Colgate Triple Action
  • Colgate Ultra Brite Advanced Whitening All IN One Clean Mint
  • Colgate Ultra White Charcoal
  • Complete Care Whole Mouth Protection
  • Cool Sense Care Plus
  • Crayola Anticavity Bubble Gum Flavor
  • Crayola Anticavity Strawberry Flavor
  • Crayola Anticavity Watermelon Flavor
  • Crest
  • Crest 3D White
  • Crest 3D White Brilliance
  • Crest 3D White Luxe
  • Crest 3D White Stain Eraser
  • Crest 3D White Whitening Therapy
  • Crest Anti-cavity
  • Crest Baking Soda And Peroxide
  • Crest Braces Care
  • Crest Cavity Protection
  • Crest Cavity Protection Cool Mint
  • Crest Cavity Protection Regular
  • Crest Complete Multi Benefit
  • Crest Complete Multi-benefit
  • Crest Complete Plus
  • Crest Complete Plus Scope
  • Crest Complete Plus Whitening
  • Crest Deep Cleanse
  • Crest Kids
  • Crest Mystic
  • Crest Plus
  • Crest Plus Baking Soda And Peroxide
  • Crest Plus Cavity Protection
  • Crest Plus Premium
  • Crest Plus Tartar Protection
  • Crest Premium Plus
  • Crest Pro Health
  • Crest Pro-health
  • Crest Pro-health Advanced
  • Crest Pro-health Advanced Complete Care
  • Crest Tartar Protection
  • Curodont Repair Fluoride Plus
  • Dawnmist
  • Dawnmist Fluoride
  • Dawnmist Fluoride Tooth
  • Dawnmist Gel Fluoride
  • Dawnmist Gel Fluoride Tooth
  • Dental Care Advance Cleaning
  • Dentalclean Blue Diamond Alcohol Free Mouthwash
  • Dentalclean Booster Kids
  • Dentalclean Dental Gel Booster Adult Use
  • Dentalclean Doctor Duck
  • Dentalclean Doctor Duck Kids Flouride Mouthwash
  • Dentalclean DR. Duck Strawberry Flouride Mouthwash
  • Dentalclean Green Diamond Alcohol Free Mouthwash
  • Dentalclean Regenerator Sensitive Dental Gel With Flouride
  • Dentalclean Regenerator Sensitive Kids
  • Dentalclean Sensitive Plus
  • Dentalclean Ultra Refreshing Extreme Ice Dental Gel
  • Dentalclean Whitening Max
  • Dentalux Anti-cavity Fluoride Whitening Mint
  • Dentalux Kids Anti-cavity Fluoride Bubble Gum
  • Dentisse
  • Dinosaur Bubble Gum Flavor Anti-cavity Fluoride Tooth
  • Doctrust Doublex Tooth
  • DR Tichenors With Extra Whitening And Tartar Control
  • DR. Jen Superpaste Nano-hydroxyapatite
  • Dubai Chocolate Flavor
  • Dubai Chocolate Fluoride Mouthwash
  • Emmi-dent Fresh
  • Emmi-dent Kids
  • Emmi-dent Whitening
  • Enamel Defense
  • Enamur Fluoride Anticavity Toothpast
  • Equate Sculpted White TP
  • Essentials Healthy Teeth And Gums
  • Essentials Whiten And Strengthen
  • Eurofresh Whitening
  • Euthymol Extraordinary Pink Whitening
  • Euthymol Whitening
  • Euthymol Whitening Gift Set
  • Euthymol Whitening Purple Corrector
  • Euthymol Whitening Set
  • Euthymol Whitening Special Gift Set
  • Euthymol Whitening Travel
  • Evo Advanced Whitening Anti-cavity Fluoride Peppermint
  • Evo Sensitive Whitening Anti-cavity Fluoride
  • Farmasi Whitening
  • Firefly Anticavity Fluoride
  • Firefly Bubble Gum Natural Fluoride
  • Firefly Strawberry Natural Fluoride
  • Fluoride Anti Caries 65g Coconut Whip Juicy Peach Mango Smoothie Summer Watermelon Hami Melom Cream Strawberries Blueberry
  • Fluoride Mouth Rinse Anticavity
  • Fluorine F-18
  • Freshen UP
  • Freshmint Anticavity Fluoride
  • Freshmint Premium Anticavity
  • Freshmint Premium Anticavity Gel
  • Gel 1100
  • Gerigentle-good Morning
  • Gleem
  • Glister Multi-action
  • Glister Multi-action Fluoride
  • Glowing White
  • Handy Solutions Crest Complete Multi-benefit Whitening Plus Scope
  • Heb
  • Heb Gleaming White
  • Hello Dragon Dazzle
  • Hello Kids Wild Strawberry
  • Hello Magical Mermaid
  • Hello Unicorn Sparkle
  • Hello Unicorn Splash
  • Hello Vitamin C Whitening
  • Hello Wild Strawberry
  • Himalaya Pink Salt Intensive Whitening Spearmint
  • Himalaya Pink Salt Purple Color Corrector Plus Intensive Whitening Toothpaste
  • Himalaya Pink Salt Purple Color Corrector Plus Intensive Whitening Vanilla Mint
  • Hismile
  • Hismile Grape Bubblegum Flavor Sodium Fluoride Anticavity Toothpast
  • Hismile Miffy Sweet Apple Flavor Sodium Fluoride Anticavity Toothpast
  • Hismile Pink Lemonade Sodium Fluoride Anticavity Toothpast
  • Humble Brush Bamboo With Fresh Mint Flouride
  • Ice Pop Flavor Sodium Fluoride Anticavity Toothpast
  • Kaylaan
  • Kids Crest
  • Kids Crest Cavity Protection
  • Kids Flouride Rinse
  • Kids Healthy Teeth
  • Kids Kare
  • Kindfill
  • Kit 2
  • Koala Pals
  • Listerine Clinical Solutions Enamel Strength Alpine Mint
  • Listerine Clinical Solutions Teeth Strength Alpine Mint
  • Listerine Smart Rinse Anticavity Fluoride Rinse - Berry Splash
  • Listerine Smart Rinse Anticavity Fluoride Rinse - Bubble Blast
  • Listerine Smart Rinse Anticavity Fluoride Rinse - Mint Shield
  • Listerine Smart Rinse Anticavity Fluoride Rinse - Pink Lemonade Flavor
  • Listerine Smart Rinse Berry Splash
  • Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint
  • Listerine Total Care Fresh Mint
  • Listerine Total Care Fresh Mint Anticavity Fluoride
  • Listerine Total Care Kids Anticavity Fluoride Rinse - Berry Splash
  • Listerine Total Care Kids Anticavity Fluoride Rinse Bubble Blast
  • Listerine Total Care Kids Anticavity Fluoride Rinse Mint Shield
  • Listerine Total Care Zero Alcohol Anticavity
  • Made BY Dentist For Kids Chew Toy (Bubblegum)
  • Made BY Dentist For Kids Chew Toy Bubblegum
  • Made BY Dentists For Kids Alien Blood
  • Made BY Dentists For Kids Cheetah Dust
  • Made BY Dentists For Kids Cheetah Dust (Strawberry)
  • Made BY Dentists For Kids Eyeball Juice
  • Made BY Dentists For Kids Eyeball Juice (Watermelon)
  • Made BY Dentists For Kids Monster Slime
  • Made BY Dentists For Kids Monster Slime Sour Apple
  • Made BY Dentists Ultra Whitening Fresh Mint
  • Made BY Dentists Ultra Whitening Professional
  • Made BY Dentists, Inc. Alien Blood
  • Made BY Dentists, Inc. Eyeball Juice
  • Made BY Dentists, Inc. Monster Slime
  • Made BY Dentists, Inc. Total Care
  • Made BY Dentists, Inc. Whitening
  • Maintenance Rinse
  • Maximum Security
  • Medichoice Premium Anticavity Fluoride
  • Mint Fluoride Tooth
  • Mintblast Cool Mint Flavor Anti Cavity Fluoride Tooth
  • Mintblast Cool Mint Flavor Anti-cavity Fluoride Tooth
  • Mipaste
  • Mipaste Plus Strawberry
  • Mipasteone Kids Blue Raspberry
  • Moon Charcoal Whitening Anticavity
  • Moon Platinum Advanced Whitening Anticavity
  • Moon Whitening Anticavity
  • Moon Whitening Gel Anticavity
  • Morning Fresh
  • Mouth Rinse
  • Natean
  • Native
  • Natural Fluoride Fresh Mint
  • Natural White
  • Natural White Sensitive Enamel Guard Alpine Mint
  • Ocean Friends Anticavity Fluoride Bubblegum Flavor
  • Ocean Friends Anticavity Fluoride Watermelon Flavor
  • Opal BY Opalescence Original
  • Opalescence Whitening
  • Orajel
  • Orajel Complete Protection
  • Orajel Gabbys Dollhouse
  • Orajel Kids Superman
  • Orajel Kidstoothpaste
  • Orajel Paw Patrol
  • Orajel Supermario
  • Oral Antivavity
  • Oral Fusion Anticavity
  • Oralline
  • Oralline Kids
  • Oralline Secure
  • Orapro Fluoride Anticavity
  • Ortho Guard
  • Ortho Super Chocolate Fluoride Mouthwash
  • Ortho Super Mint Fluoride Mouthwash
  • Ortho Super Strawberry Fluoride Mouthwash
  • Ortho Super Vanilla Fluoride Mouthwash
  • Peppermint Charcoal Anticavity Pcft6
  • Peppermint Twist
  • Pepsodent Complete Care
  • Percara Kids Bubble Gum
  • Perioe Microbiome Total Care
  • Perioe Microbiome Whitening
  • Perioe Pop Advanced Whitening Prebiotic
  • Perioe Pop Complete Protection Prebiotic
  • Perioe Whitening Essentials
  • Periosciences White Care AO Pro
  • Peroxie Care Tartar Control
  • Plak Smacker Anti Cavity Fluoride
  • Plak Smacker Great White Shark
  • Plak Smacker Great White Shark Cool Berry Flavor Anti Cavity Fluoride Gel Tooth
  • Plaque HD Anticavity Fresh Mint Flavor
  • Plaque Refresh Remineralizing Rinse Fresh Mint
  • Pop Feeling Peachy
  • Pop Gel Pumpin Strawberry
  • Pop Gel Whatzzup Watermelon
  • Pop Hint OF Mint
  • Pro-den RX
  • Quip
  • Quip Anticavity
  • Quip Anticavity Fluoride
  • Rembrandt Intense Stain
  • Rite Aid Radiant White
  • Scope
  • Sensitive Extra Whitening
  • Sensodyne Pronamel
  • Simply White
  • Sodium Fluoride F 18
  • Sprinjene
  • Super Chocolate
  • Super Chocolate Fluoride Mouthwash
  • Super Mint
  • Super Mint Fluoride Mouthwash
  • Super Strawberry
  • Super Strawberry Fluoride Mouthwash
  • Super Vanilla
  • Super Vanilla Fluoride Mouthwash
  • Tanners Tasty Cha Cha Chocolate
  • Tanners Tasty Ooh LA LA Orange
  • Tanners Tasty Vanilla Bling
  • Target Sensitive Whitening TP
  • Target UP And UP Anticavity
  • The Humble CO. Kit
  • The Natural Dentist
  • Theory
  • Therabreath Anticavity
  • Therabreath Complete Oral Rinse
  • Therabreath For Kids Anticavity Grapes Galore
  • Therabreath For Kids Anticavity Strawberry Splash
  • Therabreath For Kids Anticavity Wacky Watermelon
  • Therabreath Fresh Breath Anticavity Mild Mint
  • Therabreath Kids Anticavity Oral Rinse Bubblegum
  • Therabreath Overnight Chamomile Mint
  • Therabreath Plus Fresh Breath
  • Toms Childrens Anticavity Mouthwash Silly Strawberry
  • Toms Luminous White Fluoride Clean Mint
  • Toms OF Maine Deep Clean Spearmint
  • Toms OF Maine Whiten Plus Deep Clean Peppermint
  • Toms Teeth And Gum Health
  • Toms Whole Care Mouthwash Fresh Mint
  • TP Col OW Purple
  • TP OW Stainfighter Clean Mint
  • Treatment Rinse
  • Universal Charcoal With Aloe Vera Anti-cavity Fluoride
  • Unpaste
  • White Glo Activated Charcoal Twin Pack
  • White Glo Professional Choice Twin Pack
  • White Glo Professional White Anticavity
  • Whitening
  • Zohar Anti Cavity Mouthwash Bubble Gum Flavour
  • Zohar Anti Cavity Mouthwash Coolmint Flavour
  • Zohar Anti Cavity Mouthwash Fresh Mint Flavour
  • Zonsen Gel Fluoride
  • Zonsen Toothpaste,White
Generic Drug Synonyms and Salts
  • Sodium Fluoride F-18
  • Sodium Fluoride

FDA Approval Information

Established Pharmacologic Class (EPC): Radioactive Diagnostic Agent
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Injectable (intravenous)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2023. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2025.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Apr 15, 2025
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