Pseudoephedrine; Codeine; Guaifenesin

Drug Usage Statistics, United States, 2013 - 2022

Pseudoephedrine; Codeine; Guaifenesin Summary for 2022

Top drug rank	#0 (0)
Estimated number of prescriptions in the United States (2022)	0
Estimated number of patients in the United States (2022)	0

Average total drug cost (USD)
Per prescription	$0.00
Per day of therapy	$0.00/day
Average out-of-pocket cost (USD)
Per prescription	$0.00
Per day of therapy	$0.00/day

Total Prescriptions and Patients Per Year (2013 - 2022)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year	Rank	Change
2013	462	-
2015	489	-

Year	Rank	Change
2017	476	-
2021	403	-

Drug Cost Over Time (2013 - 2022)

Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.

Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2022)

No data available

Distribution of Days Supplied (2022)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name	Total Prescriptions (2022)
Acetaminophen; Hydrocodone	23,521,229
Tramadol	12,203,198
Oxycodone	11,314,082
Acetaminophen; Oxycodone	6,531,256
Morphine	4,101,413
Acetaminophen; Codeine	3,179,642
Brimonidine	2,126,111
Hydromorphone	1,531,449
Epinephrine	1,458,094
Brompheniramine; Dextromethorphan; Pseudoephedrine	1,039,412
Codeine; Guaifenesin	862,861
Loratadine; Pseudoephedrine	506,937
Loperamide	410,959
Fexofenadine; Pseudoephedrine	342,583
Pseudoephedrine	329,385
Homatropine; Hydrocodone	45,484
Hydrocodone; Chlorpheniramine	39,773
Guaifenesin; Pseudoephedrine	30,783
Codeine; Phenylephrine; Promethazine	26,799
Pseudoephedrine; Triprolidine	13,177
Chlorcyclizine; Pseudoephedrine	10,928
Cetirizine; Pseudoephedrine	9,084

Therapeutic Classes

N/A

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms

Tusnel
Virtussin Dac

Generic Drug Synonyms and Salts

Codeine Phosphate; Guaifenesin; Pseudoephedrine Hydrochloride
Codeine; Guaifenesin; Pseudoephedrine
Guaifenesin; Codeine Phosphate; Pseudoephedrine Hydrochloride
Guaifenesin; Codeine; Pseudoephedrine
Pseudoephedrine Hydrochloride; Codeine Phosphate; Guaifenesin
Pseudoephedrine; Codeine Phosphate; Guaifenesin
Pseudoephedrine; Codeine; Guaifenesin

FDA Approval Information

Established Pharmacologic Class (EPC):	Opioid Agonist, alpha-Adrenergic Agonist
Initial FDA approval date:	1/1/1995
First FDA applicant:	Llorens Pharmaceutical International Division
First dosage form:	Liquid (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Apr 15, 2025

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Pseudoephedrine; Codeine; Guaifenesin

Drug Usage Statistics, United States, 2013 - 2022

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