Drug Usage Statistics, United States, 2008 - 2018

Ondansetron Summary for 2018

Estimated number of prescriptions in the United States 12,240,225
Top drug rank #64 ( 19)
Average total drug cost $70.79 (USD)
Average out-of-pocket cost $8.94 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 248  71
2009 239  9
2010 210  29
2011 160  50
2012 162  2
2013 111  51
Year Rank Change
2014 117  6
2015 100  17
2016 91  9
2017 83  8
2018 64  19

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Ondansetron (this drug) 12,240,226

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Zofran Odt
  • Zuplenz
  • Ondansetron Hydrochloride And Dextrose IN Plastic Container
  • Ondansetron Hydrochloride Preservative Free
  • Zofran
  • Zofran And Dextrose IN Plastic Container
  • Zofran Preservative Free
Generic Drug Synonyms and Salts
  • Ondansetron Hydrochloride
  • Ondansetron

FDA Approval Information

Established Pharmacologic Class (EPC): Serotonin-3 Receptor Antagonist
Initial FDA approval date: 1/4/1991
First FDA applicant: Discn
First dosage form: Injectable (injection)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Which of these drugs is contraindicated in pregnancy? The Top 250 Drugs by ClinCalc Academy
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Updated Jan 18, 2021
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