Drug Usage Statistics, United States, 2013 - 2021

Niacinamide Summary for 2021

Top drug rank #359 (no previous rank)
Estimated number of prescriptions in the United States (2021) 65,343
Estimated number of patients in the United States (2021) 19,994
Average total drug cost (USD)  
Per prescription $7.28
Per day of therapy $0.27/day
Average out-of-pocket cost (USD)  
Per prescription $7.28
Per day of therapy $0.27/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 471 -
2014 468  3
2016 466 -
2017 432  34
Year Rank Change
2018 428  4
2019 455  27
2021 359 -

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

Dosage Form Strength % of Dispensed Products
Tablet/capsule 500 mg 100.0%

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Aape Continuous Renewal Mask
  • Aape Nutrient Facial Toner
  • Aape Skin Ampoule
  • AN Adc SP Intensive Moisture Essence
  • Arilac Brightening Mask Sheet Pack
  • Arocell Time Reverse K I T
  • Arocell X Belle J Super Power Cell Ampoule
  • Bellaskin Brightening Contour Essence
  • Brightuning Peptide Ampoule
  • BY Selected Hyaluron Day Serum
  • Cellbn Milky Tone-upcream
  • Cellexosome HE HR
  • Cellexosome HR
  • Cellexosome SB
  • Cica Fucoidan
  • Cosmepure Brightening Calming
  • Cosmepure Brightening Calming Toner
  • Daeng GI Meo RI Gounmo Hair Loss Care
  • DE Medicotem Illuminating White Cell Ampoule
  • Diapia Collagen Goat Milk Ampoule Mask
  • Diapia HA Aqua Shining Mask
  • DR. Cellmo
  • Edge Cutimal Cat Whitening Mask
  • Evecode Thread Lifting Mask Pack
  • Fresh Mandarin Aromatherapy Mask
  • Juveheal W Ampoule
  • Lebody Lab Renewal Dual Effect Hyaluronic Serum
  • Lebody Lab Renewal Dual Effect Idebenone Serum
  • Lebody Lab Renewal Dual Effect Peptide Serum
  • Mustus Daily Harvest Squeeze Tone UP Mask Pack
  • Pahaba Control
  • Pahaba Solution
  • Papa Recipe Bombee Brightening Honey Mask Pack
  • Rgo Hydration Toner
  • Royal Ginseng Essence
  • Royal Ginseng Toner
  • Royal Ginsengcream
  • Royal Ginsenglotion
  • Sferangs Vita C Capsulebooster
  • Siseundeusi Luminant
  • Siseundeusi Luminant Mask Pack Step2(Whitening)
  • Skin Project YA Cooling Celluven Mask
  • The Skin House Vital Bright Emulsion
  • The Skin House Vital Bright Eyecream
  • The Skin House Vital Bright Toner
  • The Skin House Vital Brightcream
  • The Skin House Vital Brightemulsion
  • The Skin House Vital Brightserum
  • The Skinhouse Aloe Soothing Vitamin
  • The Skinhouse White Tightening Serum
  • The Skinhouse White Tightening Toner
  • The Skinhouse White Tighteningcream
  • The Skinhouse White Tighteningemulsion
  • Ultra V Aqua Shine Mask
  • Vita C Bright Eyecream
  • Vita C Bright Serum
  • Vita C Bright Toner
  • Vita C Brightcream
  • W.Skin White Glutathione Tone UP
Generic Drug Synonyms and Salts
  • Niacinamide

FDA Approval Information

Established Pharmacologic Class (EPC): N/A
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Suspension (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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