Nebivolol

Drug Usage Statistics, United States, 2014 - 2023

Nebivolol Summary for 2023

Top drug rank	#191 ( 18)
Estimated number of prescriptions in the United States (2023)	2,568,389
Estimated number of patients in the United States (2023)	844,304

Average total drug cost (USD)
Per prescription	$83.00
Per day of therapy	$1.52/day
Average out-of-pocket cost (USD)
Per prescription	$28.26
Per day of therapy	$0.46/day

Total Prescriptions and Patients Per Year (2014 - 2023)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year	Rank	Change
2014	141	32
2015	150	9
2016	128	22
2017	149	21
2018	199	50

Year	Rank	Change
2019	192	7
2020	239	47
2021	244	5
2022	173	71
2023	191	18

Drug Cost Over Time (2014 - 2023)

Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.

Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2023)

Dosage Form	Strength	% of Dispensed Products
Tablet/capsule	5 mg	43.7%
Tablet/capsule	10 mg	41.5%
Tablet/capsule	2.5 mg	7.4%
Tablet/capsule	20 mg	7.4%

Distribution of Days Supplied (2023)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name	Total Prescriptions (2023)
Metoprolol	59,547,256
Carvedilol	16,566,782
Propranolol	9,699,273
Atenolol	9,235,306
Timolol	2,946,884
Nebivolol (this drug)	2,568,390
Bisoprolol	1,816,701
Dorzolamide; Timolol	1,620,621
Labetalol	1,555,592

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms

Bystolic

Generic Drug Synonyms and Salts

Nebivolol Hydrochloride
Nebivolol

FDA Approval Information

Established Pharmacologic Class (EPC):	beta-Adrenergic Blocker
Initial FDA approval date:	12/17/2007
First FDA applicant:	Rx
First dosage form:	Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2023. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2025.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Which of these drugs is contraindicated in pregnancy? The Top 250 Drugs by ClinCalc Academy

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Updated Apr 15, 2025

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