Drug Usage Statistics, United States, 2008 - 2018

Letrozole Summary for 2018

Estimated number of prescriptions in the United States 2,377,550
Top drug rank #223 ( 81)
Average total drug cost $200.53 (USD)
Average out-of-pocket cost $7.71 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 314  20
2009 288  26
2010 302  14
2011 305  3
2012 328  23
2013 357  29
Year Rank Change
2014 297  60
2015 270  27
2016 306  36
2017 304  2
2018 223  81

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Letrozole (this drug) 2,377,550
Anastrozole 2,292,337

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Femara
Generic Drug Synonyms and Salts
  • Letrozole

FDA Approval Information

Established Pharmacologic Class (EPC): Aromatase Inhibitor
Initial FDA approval date: 7/25/1997
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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