Drug Usage Statistics, United States, 2013 - 2021

Labetalol Summary for 2021

Top drug rank #213 ( 3)
Estimated number of prescriptions in the United States (2021) 2,019,527
Estimated number of patients in the United States (2021) 507,522
Average total drug cost (USD)  
Per prescription $36.25
Per day of therapy $0.71/day
Average out-of-pocket cost (USD)  
Per prescription $13.63
Per day of therapy $0.36/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 188  13
2014 217  29
2015 237  20
2016 236  1
Year Rank Change
2017 217  19
2018 231  14
2019 199  32
2020 210  11
2021 213  3

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

Dosage Form Strength % of Dispensed Products
Tablet/capsule 100 mg 45.2%
Tablet/capsule 200 mg 36.1%
Tablet/capsule 300 mg 18.7%

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2021)
Metoprolol 65,529,551
Carvedilol 21,782,178
Atenolol 14,107,488
Propranolol 7,993,156
Timolol 3,406,226
Dorzolamide; Timolol 2,518,854
Labetalol (this drug) 2,019,527
Nebivolol 1,554,153

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Normodyne
  • Trandate
  • Labetalol Hydrochloride IN Dextrose
  • Labetalol Hydrochloride IN Sodium Chloride
Generic Drug Synonyms and Salts
  • Labetalol Hydrochloride
  • Labetalol

FDA Approval Information

Established Pharmacologic Class (EPC): beta-Adrenergic Blocker
Initial FDA approval date: 8/1/1984
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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