Hydrochlorothiazide; Lisinopril

Drug Usage Statistics, United States, 2007 - 2017

Number of Prescriptions Over Time (2007 - 2017)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2007 44  5
2008 44 0
2009 30  14
2010 41  11
2011 39  2
2012 35  4
Year Rank Change
2013 26  9
2014 37  11
2015 37 0
2016 53  16
2017 44  9

Patient Out-Of-Pocket Cost Over Time (2007 - 2017)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2017)
Lisinopril 104,779,319
Hydrochlorothiazide 42,037,081
Hydrochlorothiazide; Lisinopril (this drug) 16,687,919
Hydrochlorothiazide; Losartan Potassium 11,752,545
Hydrochlorothiazide; Triamterene 7,631,431
Benazepril Hydrochloride 7,163,351
Enalapril Maleate 6,121,954
Hydrochlorothiazide; Valsartan 5,341,254
Ramipril 5,318,556
Amlodipine Besylate; Benazepril Hydrochloride 3,896,258
Quinapril 1,536,944
Bisoprolol Fumarate; Hydrochlorothiazide 967,296
Benazepril Hydrochloride; Hydrochlorothiazide 844,857

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Lisinopril And Hydrochlorothiazide
  • Prinzide
  • Zestoretic
Generic Drug Synonyms and Salts
  • Lisinopril; Hydrochlorothiazide
  • Hydrochlorothiazide; Lisinopril

FDA Approval Information

Established Pharmacologic Class (EPC): Thiazide Diuretic, Angiotensin Converting Enzyme Inhibitor
Initial FDA approval date: 2/16/1989
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2007-2017. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 20.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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