Hydrochlorothiazide; Lisinopril

Drug Usage Statistics, United States, 2008 - 2018

Hydrochlorothiazide; Lisinopril Summary for 2018

Estimated number of prescriptions in the United States 15,932,877
Top drug rank #51 ( 7)
Average total drug cost $17.35 (USD)
Average out-of-pocket cost $4.86 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 44 0
2009 30  14
2010 41  11
2011 39  2
2012 35  4
2013 26  9
Year Rank Change
2014 37  11
2015 37 0
2016 53  16
2017 44  9
2018 51  7

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Lisinopril 97,608,879
Hydrochlorothiazide 40,575,076
Hydrochlorothiazide; Lisinopril (this drug) 15,932,877
Hydrochlorothiazide; Losartan Potassium 13,880,262
Hydrochlorothiazide; Triamterene 6,007,405
Benazepril Hydrochloride 5,920,053
Enalapril Maleate 5,182,854
Ramipril 3,989,667
Amlodipine Besylate; Benazepril Hydrochloride 3,284,178
Hydrochlorothiazide; Valsartan 3,261,560
Bisoprolol Fumarate; Hydrochlorothiazide 1,556,623
Quinapril 1,012,588
Benazepril Hydrochloride; Hydrochlorothiazide 1,001,353

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Lisinopril And Hydrochlorothiazide
  • Prinzide
  • Zestoretic
Generic Drug Synonyms and Salts
  • Lisinopril; Hydrochlorothiazide
  • Hydrochlorothiazide; Lisinopril

FDA Approval Information

Established Pharmacologic Class (EPC): Thiazide Diuretic, Angiotensin Converting Enzyme Inhibitor
Initial FDA approval date: 2/16/1989
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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