Drug Usage Statistics, United States, 2008 - 2018

Hydrochlorothiazide Summary for 2018

Estimated number of prescriptions in the United States 40,575,075
Top drug rank #13 ( 1)
Average total drug cost $7.85 (USD)
Average out-of-pocket cost $3.26 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 8  1
2009 8 0
2010 9  1
2011 9 0
2012 10  1
2013 10 0
Year Rank Change
2014 10 0
2015 11  1
2016 12  1
2017 12 0
2018 13  1

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Hydrochlorothiazide (this drug) 40,575,076
Hydrochlorothiazide; Lisinopril 15,932,877
Hydrochlorothiazide; Losartan Potassium 13,880,262
Hydrochlorothiazide; Triamterene 6,007,405
Hydrochlorothiazide; Valsartan 3,261,560
Bisoprolol Fumarate; Hydrochlorothiazide 1,556,623
Benazepril Hydrochloride; Hydrochlorothiazide 1,001,353

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Esidrix
  • Hydro-d
  • Hydrochlorothiazide Intensol
  • Hydrodiuril
  • Microzide
  • Oretic
  • Zide
Generic Drug Synonyms and Salts
  • Hydrochlorothiazide

FDA Approval Information

Established Pharmacologic Class (EPC): Thiazide Diuretic
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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