Glyburide; Metformin Hydrochloride

Drug Usage Statistics, United States, 2006 - 2016

Number of Prescriptions Over Time (2006 - 2016)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2006 120  1
2007 121  1
2008 122  1
2009 136  14
2010 185  49
Year Rank Change
2011 215  30
2012 177  38
2013 196  19
2014 232  36
2015 296  64

Patient Out-Of-Pocket Cost Over Time (2006 - 2016)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2016)
Metformin Hydrochloride 81,305,416
Glipizide 17,884,980
Glimepiride 12,432,147
Glyburide 3,591,159
Metformin Hydrochloride; Sitagliptin Phosphate 3,150,401

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Glucovance
  • Glyburide And Metformin Hydrochloride
Generic Drug Synonyms and Salts
  • Glyburide; Metformin Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Sulfonylurea, Biguanide
Initial FDA approval date: 7/31/2000
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2006-2016. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 19.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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