Fluoxetine Hydrochloride

Drug Usage Statistics, United States, 2008 - 2018

Fluoxetine Hydrochloride Summary for 2018

Estimated number of prescriptions in the United States 25,619,277
Top drug rank #23 ( 8)
Average total drug cost $42.39 (USD)
Average out-of-pocket cost $9.26 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 23  5
2009 23 0
2010 30  7
2011 29  1
2012 21  8
2013 31  10
Year Rank Change
2014 34  3
2015 20  14
2016 29  9
2017 31  2
2018 23  8

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Sertraline Hydrochloride 38,383,043
Escitalopram Oxalate 25,978,773
Fluoxetine Hydrochloride (this drug) 25,619,277
Trazodone Hydrochloride 23,889,625
Citalopram 22,224,263
Paroxetine 11,228,908

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Fluoxetine
  • Prozac
  • Prozac Weekly
  • Sarafem
  • Selfemra
Generic Drug Synonyms and Salts
  • Fluoxetine Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Serotonin Reuptake Inhibitor
Initial FDA approval date: 12/29/1987
First FDA applicant: Rx
First dosage form: Capsule (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Which of these drugs is contraindicated in pregnancy? The Top 250 Drugs by ClinCalc Academy
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Updated Jan 18, 2021
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