Ethinyl Estradiol; Norethindrone

Drug Usage Statistics, United States, 2013 - 2022

Ethinyl Estradiol; Norethindrone Summary for 2022

Top drug rank #80 ( 28)
Estimated number of prescriptions in the United States (2022) 8,582,372
Estimated number of patients in the United States (2022) 2,406,285
 
Average total drug cost (USD)  
Per prescription $79.60
Per day of therapy $1.52/day
Average out-of-pocket cost (USD)  
Per prescription $3.28
Per day of therapy $0.09/day

Total Prescriptions and Patients Per Year (2013 - 2022)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 59  5
2014 60  1
2015 60 0
2016 54  6
2017 52  2
Year Rank Change
2018 57  5
2019 42  15
2020 45  3
2021 52  7
2022 80  28

Drug Cost Over Time (2013 - 2022)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2022)

No data available

Distribution of Days Supplied (2022)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2022)
Estradiol 12,622,776
Ethinyl Estradiol; Norethindrone (this drug) 8,582,372
Ethinyl Estradiol; Levonorgestrel 4,846,344
Norethindrone 4,337,337
Ethinyl Estradiol; Etonogestrel 2,217,839
Medroxyprogesterone 810,406
Ethinyl Estradiol; Norelgestromin 351,420

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Alyacen 1/35
  • Alyacen 7/7/7
  • Aranelle
  • Balziva-21
  • Balziva-28
  • Brevicon 21-day
  • Brevicon 28-day
  • Briellyn
  • Cyclafem 0.5/35
  • Cyclafem 1/35
  • Cyclafem 7/7/7
  • Cyonanz
  • Dasetta 1/35
  • Dasetta 7/7/7
  • Femcon FE
  • Gencept 10/11-21
  • Gencept 10/11-28
  • Gildagia
  • Kaitlib FE
  • Modicon 21
  • Modicon 28
  • N.E.E. 1/35 21
  • N.E.E. 1/35 28
  • Nexesta FE
  • Norcept-e 1/35 21
  • Norcept-e 1/35 28
  • Norethin 1/35e-21
  • Norethin 1/35e-28
  • Norethindrone And Ethinyl Estradiol
  • Norethindrone And Ethinyl Estradiol (10/11)
  • Norethindrone And Ethinyl Estradiol (7/14)
  • Norethindrone And Ethinyl Estradiol And Ferrous Fumarate
  • Norinyl 1+35 21-day
  • Norinyl 1+35 28-day
  • Nortrel 0.5/35-21
  • Nortrel 0.5/35-28
  • Nortrel 1/35-21
  • Nortrel 1/35-28
  • Nortrel 7/7/7
  • Nylia 1/35
  • Nylia 7/7/7
  • Ortho-novum 1/35-21
  • Ortho-novum 1/35-28
  • Ortho-novum 10/11-21
  • Ortho-novum 10/11-28
  • Ortho-novum 7/14-21
  • Ortho-novum 7/14-28
  • Ortho-novum 7/7/7-21
  • Ortho-novum 7/7/7-28
  • Ovcon-35
  • Ovcon-50
  • Philith
  • Pirmella 1/35
  • Pirmella 7/7/7
  • Rhuzdah
  • Tri-norinyl 21-day
  • Tri-norinyl 28-day
  • Vyfemla
  • Wera
  • Aurovela 1.5/30
  • Aurovela 1/20
  • Aurovela 24 FE
  • Aurovela FE 1.5/30
  • Aurovela FE 1/20
  • Blisovi 24 FE
  • Blisovi FE 1.5/30
  • Blisovi FE 1/20
  • Chabelina FE
  • Estrostep 21
  • Estrostep FE
  • Femhrt
  • Finzala
  • Fyavolv
  • Gemmily
  • Gildess 1.5/30
  • Gildess 1/20
  • Gildess 24 FE
  • Gildess FE 1.5/30
  • Gildess FE 1/20
  • Hailey 1.5/30
  • Hailey 24 FE
  • Hailey FE 1.5/30
  • Hailey FE 1/20
  • Junel 1.5/30
  • Junel 1/20
  • Junel FE 1.5/30
  • Junel FE 1/20
  • Larin 1.5/30
  • Larin 1/20
  • Larin 24 FE
  • Larin FE 1.5/30
  • Larin FE 1/20
  • Leribane
  • LO Loestrin FE
  • LO Minastrin FE
  • Loestrin 21 1.5/30
  • Loestrin 21 1/20
  • Loestrin 24 FE
  • Loestrin FE 1.5/30
  • Loestrin FE 1/20
  • Merzee
  • Mibelas 24 FE
  • Microgestin 1.5/30
  • Microgestin 1/20
  • Microgestin FE 1.5/30
  • Microgestin FE 1/20
  • Minastrin 24 FE
  • Norethindrone Acetate And Ethinyl Estradiol
  • Norethindrone Acetate And Ethinyl Estradiol And Ethinyl Estradiol And Ferrous Fumarate
  • Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate
  • Norlestrin 21 1/50
  • Norlestrin 21 2.5/50
  • Norlestrin 28 1/50
  • Oshih
  • Taytulla
  • Tri-legest 21
  • Tri-legest FE
  • Nortrel
  • Jinteli
  • Junel
  • Loestrin
  • Balziva
  • Leena
  • Necon
  • Wymzya FE
  • Zenchent FE
Generic Drug Synonyms and Salts
  • Ethinyl Estradiol; Norethindrone Acetate
  • Norethindrone Acetate; Ethinyl Estradiol
  • Norethindrone; Ethinyl Estradiol
  • Ethinyl Estradiol; Norethindrone

FDA Approval Information

Established Pharmacologic Class (EPC): Estrogen, Progestin
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Tablet (oral-21)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Sep 12, 2021
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