Ethinyl Estradiol; Norelgestromin

Drug Usage Statistics, United States, 2014 - 2024

Ethinyl Estradiol; Norelgestromin Summary for 2024

Top drug rank	#269 ( 16)
Estimated number of prescriptions in the United States (2024)	1,194,977
Estimated number of patients in the United States (2024)	480,109

Average total drug cost (USD)
Per prescription	$136.01
Per day of therapy	$5.19/day
Average out-of-pocket cost (USD)
Per prescription	$3.78
Per day of therapy	$0.02/day

Total Prescriptions and Patients Per Year (2014 - 2024)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year	Rank	Change
2014	382	30
2015	374	8
2016	419	45
2017	378	41
2018	377	1
2019	346	31

Year	Rank	Change
2020	349	3
2021	306	43
2022	303	3
2023	285	18
2024	269	16

Drug Cost Over Time (2014 - 2024)

Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.

Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2024)

No data available

Distribution of Days Supplied (2024)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name	Total Prescriptions (2024)
Estradiol	12,891,354
Ethinyl Estradiol; Norethindrone	10,330,394
Norethindrone	5,482,819
Ethinyl Estradiol; Levonorgestrel	3,541,217
Ethinyl Estradiol; Etonogestrel	3,372,586
Medroxyprogesterone	1,744,511
Ethinyl Estradiol; Norelgestromin (this drug)	1,194,977

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms

Gwyn LO
Onsura
Ortho Evra
Xulane
Zafemy

Generic Drug Synonyms and Salts

Norelgestromin; Ethinyl Estradiol
Ethinyl Estradiol; Norelgestromin

FDA Approval Information

Established Pharmacologic Class (EPC):	Estrogen, Progestin
Initial FDA approval date:	11/20/2001
First FDA applicant:	Discn
First dosage form:	Film, Extended Release (transdermal)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Apr 15, 2025

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Ethinyl Estradiol; Norelgestromin

Drug Usage Statistics, United States, 2014 - 2024

ClinCalc.com » Pharmacy » ClinCalc DrugStats » Ethinyl Estradiol; Norelgestromin