Ethinyl Estradiol; Levonorgestrel

Drug Usage Statistics, United States, 2013 - 2022

Ethinyl Estradiol; Levonorgestrel Summary for 2022

Top drug rank #128 ( 16)
Estimated number of prescriptions in the United States (2022) 4,846,343
Estimated number of patients in the United States (2022) 1,327,012
 
Average total drug cost (USD)  
Per prescription $38.37
Per day of therapy $0.53/day
Average out-of-pocket cost (USD)  
Per prescription $9.04
Per day of therapy $0.14/day

Total Prescriptions and Patients Per Year (2013 - 2022)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 126  24
2014 160  34
2015 95  65
2016 116  21
2017 139  23
Year Rank Change
2018 138  1
2019 124  14
2020 159  35
2021 144  15
2022 128  16

Drug Cost Over Time (2013 - 2022)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2022)

Dosage Form Strength % of Dispensed Products
Tablet/capsule 0.15-0.03 mg 83.3%
Tablet/capsule 20/100 other 16.7%

Distribution of Days Supplied (2022)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2022)
Estradiol 12,622,776
Ethinyl Estradiol; Norethindrone 8,582,372
Ethinyl Estradiol; Levonorgestrel (this drug) 4,846,344
Norethindrone 4,337,337
Ethinyl Estradiol; Etonogestrel 2,217,839
Medroxyprogesterone 810,406
Ethinyl Estradiol; Norelgestromin 351,420

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Afirmelle
  • Alesse
  • Altavera
  • Ashlyna
  • Aviane-21
  • Aviane-28
  • Ayuna
  • Balcoltra
  • Cerinta
  • Daysee
  • Dolishale
  • Elifemme
  • Enpresse-21
  • Enpresse-28
  • Falmina
  • Fayosim
  • Iclevia
  • Introvale
  • Jaimiess
  • Kurvelo
  • Lessina-21
  • Lessina-28
  • Levlite
  • Levonest
  • Levonorgestrel And Ethinyl Estradiol
  • Levonorgestrel And Ethinyl Estradiol And Ethinyl Estradiol
  • Levonorgestrel And Ethinyl Estradiol And Ferrous Fumarate
  • Levora 0.15/30-21
  • Levora 0.15/30-28
  • LO Simpesse
  • Loseasonique
  • Lybrel
  • Marlissa
  • Minzoya
  • Myzilra
  • Nordette-21
  • Nordette-28
  • Orsythia
  • Portia-21
  • Portia-28
  • Preven Emergency Contraceptive Kit
  • Quartette
  • Quasense
  • Seasonale
  • Seasonique
  • Setlakin
  • Simpesse
  • Sylevia
  • Triphasil-21
  • Triphasil-28
  • Trivora-21
  • Trivora-28
  • Twirla
  • Tyblume
  • Vienva
  • Amethyst
  • Aubra EQ
  • Aviane
  • Chateal EQ
  • Enpresse
  • Lessina
  • Levora
  • Lutera
  • Portia
  • Sronyx
  • Trivora
  • Vienva TM
Generic Drug Synonyms and Salts
  • Ethinyl Estradiol; Levonorgestrel
  • Levonorgestrel; Ethinyl Estradiol

FDA Approval Information

Established Pharmacologic Class (EPC): Progestin, Progestin-containing Intrauterine Device, Estrogen
Initial FDA approval date: 5/10/1982
First FDA applicant: Discn
First dosage form: Tablet (oral-21)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Which of these drugs is contraindicated in pregnancy? The Top 250 Drugs by ClinCalc Academy
 
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Updated Sep 12, 2021
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