Estradiol

Drug Usage Statistics, United States, 2008 - 2018

Estradiol Summary for 2018

Estimated number of prescriptions in the United States 13,583,025
Top drug rank #54 ( 7)
Average total drug cost $89.44 (USD)
Average out-of-pocket cost $21.1 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 75  1
2009 71  4
2010 61  10
2011 82  21
2012 66  16
2013 61  5
Year Rank Change
2014 64  3
2015 59  5
2016 59 0
2017 61  2
2018 54  7

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Estradiol (this drug) 13,583,026
Estrogens, Conjugated 2,436,387

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Alora
  • Climara
  • Divigel
  • Elestrin
  • Esclim
  • Estrace
  • Estraderm
  • Estring
  • Estrogel
  • Evamist
  • Fempatch
  • Gynodiol
  • Imvexxy
  • Innofem
  • Menostar
  • Minivelle
  • Vagifem
  • Vivelle
  • Vivelle-dot
  • Femring
  • Femtrace
  • Depo-estradiol
  • Estrasorb
Generic Drug Synonyms and Salts
  • Estradiol Acetate
  • Estradiol Cypionate
  • Estradiol Hemihydrate
  • Estradiol

FDA Approval Information

Established Pharmacologic Class (EPC): Estrogen
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.0. Read more about the ClinCalc DrugStats database.

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Updated Nov 19, 2020
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