Drug Usage Statistics, United States, 2008 - 2018

Epinephrine Summary for 2018

Estimated number of prescriptions in the United States 2,036,712
Top drug rank #242 ( 21)
Average total drug cost $817.11 (USD)
Average out-of-pocket cost $154.47 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 427  56
2009 394  33
2010 401  7
2011 365  36
2012 356  9
2013 312  44
Year Rank Change
2014 293  19
2015 314  21
2016 253  61
2017 263  10
2018 242  21

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Adrenaclick
  • Adrenalin
  • Auvi-q
  • Bronkaid Mist
  • Epi E Z Pen JR
  • Epinephrine (Autoinjector)
  • Epinephrine (Copackaged)
  • Epipen
  • Epipen E Z Pen
  • Epipen JR.
  • Primatene Mist
  • Sus-phrine Sulfite Free
  • Symjepi
  • Twinject 0.15
  • Twinject 0.3
  • Bronitin Mist
  • Medihaler-epi
Generic Drug Synonyms and Salts
  • Epinephrine Bitartrate
  • Epinephrine Hydrochloride
  • Epinephrine

FDA Approval Information

Established Pharmacologic Class (EPC): alpha-Adrenergic Agonist, beta-Adrenergic Agonist, Catecholamine
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Aerosol, Metered (inhalation)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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