Dorzolamide; Timolol

Drug Usage Statistics, United States, 2013 - 2021

Dorzolamide; Timolol Summary for 2021

Top drug rank #191 ( 4)
Estimated number of prescriptions in the United States (2021) 2,518,853
Estimated number of patients in the United States (2021) 788,637
Average total drug cost (USD)  
Per prescription $46.90
Per day of therapy $0.90/day
Average out-of-pocket cost (USD)  
Per prescription $22.51
Per day of therapy $0.26/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 262  48
2014 286  24
2015 234  52
2016 199  35
Year Rank Change
2017 237  38
2018 252  15
2019 208  44
2020 195  13
2021 191  4

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

Dosage Form Strength % of Dispensed Products
Drops 2/0.5% 66.7%
Solution 2-0.5% 33.3%

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2021)
Metoprolol 65,529,551
Carvedilol 21,782,178
Atenolol 14,107,488
Propranolol 7,993,156
Timolol 3,406,226
Dorzolamide; Timolol (this drug) 2,518,854
Dorzolamide 2,277,156
Labetalol 2,019,527
Nebivolol 1,554,153

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Cosopt
  • Cosopt PF
  • Dorzolamide Hydrochloride And Timolol Maleate
Generic Drug Synonyms and Salts
  • Dorzolamide Hydrochloride; Timolol Maleate
  • Dorzolamide Hydrochloride; Timolol Maleate; Brimonidine Tartrate
  • Dorzolamide Hydrochloride; Timolol Maleate; Latanoprost
  • Timolol Maleate; Dorzolamide Hydrochloride
  • Dorzolamide; Timolol

FDA Approval Information

Established Pharmacologic Class (EPC): Carbonic Anhydrase Inhibitor, beta-Adrenergic Blocker
Initial FDA approval date: 4/7/1998
First FDA applicant: Rx
First dosage form: Solution/Drops (ophthalmic)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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