Divalproex Sodium

Drug Usage Statistics, United States, 2008 - 2018

Divalproex Sodium Summary for 2018

Estimated number of prescriptions in the United States 5,275,298
Top drug rank #131 ( 5)
Average total drug cost $114.88 (USD)
Average out-of-pocket cost $11.07 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 128  28
2009 100  28
2010 125  25
2011 136  11
2012 117  19
2013 119  2
Year Rank Change
2014 102  17
2015 120  18
2016 129  9
2017 126  3
2018 131  5

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Gabapentin 45,586,654
Lamotrigine 11,582,775
Divalproex Sodium (this drug) 5,275,298
Oxcarbazepine 3,915,509
Lithium 3,077,612
Carbamazepine 2,840,744
Phenytoin 1,643,498
Primidone 1,437,305

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Depakote
  • Depakote CP
  • Depakote ER
Generic Drug Synonyms and Salts
  • Divalproex Sodium

FDA Approval Information

Established Pharmacologic Class (EPC): Anti-epileptic Agent, Mood Stabilizer
Initial FDA approval date: 3/10/1983
First FDA applicant: Rx
First dosage form: Tablet, Delayed Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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