Diphenhydramine Hydrochloride

Drug Usage Statistics, United States, 2006 - 2016

Number of Prescriptions Over Time (2006 - 2016)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2006 220  34
2007 175  45
2008 238  63
2009 248  10
2010 273  25
2011 249  24
Year Rank Change
2012 259  10
2013 275  16
2014 198  77
2015 221  23
2016 210  11

Patient Out-Of-Pocket Cost Over Time (2006 - 2016)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Antitussive
  • Beldin
  • Belix
  • Benadryl
  • Benadryl Preservative Free
  • Benylin
  • Dibenil
  • Diphen
  • Diphenhydramine Hydrochloride Preservative Free
  • Diphenydramine Hydrochloride
  • Hydramine
  • Silphen
  • Vicks Formula 44
Generic Drug Synonyms and Salts
  • Diphenhydramine Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): N/A
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Capsule (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2006-2016. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 19.0. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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