Diclofenac; Misoprostol

Drug Usage Statistics, United States, 2014 - 2024

Diclofenac; Misoprostol Summary for 2024

Top drug rank	#382 ( 28)
Estimated number of prescriptions in the United States (2024)	16,243
Estimated number of patients in the United States (2024)	16,243

Average total drug cost (USD)
Per prescription	$40.59
Per day of therapy	$4.06/day
Average out-of-pocket cost (USD)
Per prescription	$40.59
Per day of therapy	$4.06/day

Total Prescriptions and Patients Per Year (2014 - 2024)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year	Rank	Change
2014	424	18
2015	261	163
2016	433	172
2017	438	5
2018	430	8

Year	Rank	Change
2019	462	32
2021	342	-
2022	368	26
2023	354	14
2024	382	28

Drug Cost Over Time (2014 - 2024)

Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.

Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2024)

No data available

Distribution of Days Supplied (2024)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name	Total Prescriptions (2024)
Meloxicam	19,699,162
Ibuprofen	16,850,357
Aspirin	12,818,518
Diclofenac	10,486,740
Celecoxib	8,925,992
Naproxen	5,874,206
Ketorolac	2,383,166
Nabumetone	1,038,360
Indomethacin	720,259
Etodolac	436,916
Sulindac	207,810
Piroxicam	33,436
Oxaprozin	20,503
Diclofenac; Misoprostol (this drug)	16,244

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms

Arthrotec

Generic Drug Synonyms and Salts

Diclofenac Sodium; Misoprostol
Misoprostol; Diclofenac Sodium
Diclofenac; Misoprostol

FDA Approval Information

Established Pharmacologic Class (EPC):	Nonsteroidal Anti-inflammatory Drug, Prostaglandin E1 Analog
Initial FDA approval date:	12/24/1997
First FDA applicant:	Rx
First dosage form:	Tablet, Delayed Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Diclofenac; Misoprostol

Drug Usage Statistics, United States, 2014 - 2024

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