Dextromethorphan Hydrobromide; Promethazine Hydrochloride

Drug Usage Statistics, United States, 2008 - 2018

Dextromethorphan Hydrobromide; Promethazine Hydrochloride Summary for 2018

Estimated number of prescriptions in the United States 867,626
Top drug rank #342 ( 28)
Average total drug cost $9.27 (USD)
Average out-of-pocket cost $5.33 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 606  10
2009 448  158
2010 664  216
2011 684  20
2013 360 -
Year Rank Change
2014 357  3
2015 349  8
2016 335  14
2017 370  35
2018 342  28

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Promethazine Hydrochloride 4,171,552
Brompheniramine Maleate; Dextromethorphan Hydrobromide; Pseudoephedrine Hydrochloride 1,228,853
Dextromethorphan Hydrobromide; Promethazine Hydrochloride (this drug) 867,626
Codeine Phosphate; Promethazine Hydrochloride 745,667
Prochlorperazine 536,923

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Pherazine DM
  • Prometh W/ Dextromethorphan
  • Promethazine DM
  • Promethazine Hydrochloride And Dextromethorphan Hydrobromide
  • Promethazine W/ Dextromethorphan
Generic Drug Synonyms and Salts
  • Promethazine Hydrochloride; Dextromethorphan Hydrobromide
  • Dextromethorphan Hydrobromide; Promethazine Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist, Phenothiazine
Initial FDA approval date: 4/2/1984
First FDA applicant: Discn
First dosage form: Syrup (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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