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Dextromethorphan; Guaifenesin; Pseudoephedrine

Drug Usage Statistics, United States, 2014 - 2024

ClinCalc.com » Pharmacy » ClinCalc DrugStats » Dextromethorphan; Guaifenesin; Pseudoephedrine

Dextromethorphan; Guaifenesin; Pseudoephedrine Summary for 2024

Top drug rank #389 ( 25)
Estimated number of prescriptions in the United States (2024) 6,963
Estimated number of patients in the United States (2024) 6,963
 
Average total drug cost (USD)  
Per prescription $19.00
Per day of therapy $0.00/day
Average out-of-pocket cost (USD)  
Per prescription $0.00
Per day of therapy $0.00/day

Total Prescriptions and Patients Per Year (2014 - 2024)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2014 488  42
2015 472  16
2017 458 -
Year Rank Change
2018 487  29
2023 364 -
2024 389  25

Drug Cost Over Time (2014 - 2024)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypertensive costing $30 would be $1 per day.
  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2024)

No data available

Distribution of Days Supplied (2024)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name Total Prescriptions (2024)
Brimonidine 2,999,164
Epinephrine 1,835,103
Dextromethorphan; Promethazine 1,773,420
Loratadine; Pseudoephedrine 754,456
Brompheniramine; Dextromethorphan; Pseudoephedrine 702,500
Pseudoephedrine 371,195
Dextromethorphan 326,898
Dextromethorphan; Triprolidine 79,404
Chlorpheniramine; Dextromethorphan; Phenylephrine 69,747
Dextromethorphan; Guaifenesin 45,121
Fexofenadine; Pseudoephedrine 40,611
Brompheniramine; Dextromethorphan; Phenylephrine 28,853
Dexbrompheniramine; Dextromethorphan; Phenylephrine 19,157
Dextromethorphan; Guaifenesin; Phenylephrine 18,373
Dextromethorphan; Phenylephrine; Pyrilamine 17,542
Dextromethorphan; Guaifenesin; Pseudoephedrine (this drug) 6,963
Chlophedianol; Dexbrompheniramine; Pseudoephedrine 5,097
Dextromethorphan; Phenylephrine; Triprolidine 2,319

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Actinel
  • Actinel Pediatric
  • Actispec Pse
  • Capmist DM
  • Poly-vent DM
  • Tusnel
  • Tusnel DM
Generic Drug Synonyms and Salts
  • Dextromethorphan Hydrobromide; Guaifenesin; Pseudoephedrine Hydrochloride
  • Guaifenesin; Dextromethorphan Hydrobromide; Pseudoephedrine Hydrochloride
  • Guaifenesin; Pseudoephedrine Hydrochloride; Dextromethorphan Hydrobromide
  • Pseudoephedrine Hydrochloride; Guaifenesin; Dextromethorphan Hydrobromide
  • Dextromethorphan; Guaifenesin; Pseudoephedrine

FDA Approval Information

Established Pharmacologic Class (EPC): Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-Adrenergic Agonist
Initial FDA approval date: 1/1/1993
First FDA applicant: Llorens Pharmaceutical International Division
First dosage form: Solution/ Drops (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2014-2024. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2026.08. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

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Updated Apr 15, 2025
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